Raman spectroscopy of blood plasma for cancer diagnosis

O. Cherkasova; A. Mankova; D. Vrazhnov

doi:10.1117/12.2613925

2 December 2021 Raman spectroscopy of blood plasma for cancer diagnosis

O. Cherkasova, A. Mankova, D. Vrazhnov

Proceedings Volume 12086, XV International Conference on Pulsed Lasers and Laser Applications; 120861M (2021) https://doi.org/10.1117/12.2613925
Event: XV International Conference on Pulsed Lasers and Laser Applications, 2021, Tomsk, Russian Federation

Abstract

Raman spectra of blood plasma were studied in the dynamics of the experimental glioma. We used a DXR Raman Microscope (Thermo Scientific), excitation wavelengths of 532 nm, range 80–3200 cm^–1. Each sample of blood plasma was a droplet with a volume of 10 μL placed on a special aluminum plate. Machine learning methods were used to identify the most informative frequencies associated with cancer molecular markers. The most significant changes in the Raman spectra are observed in the 900–1700 cm_–1 range.

Citation Download Citation

O. Cherkasova, A. Mankova, and D. Vrazhnov "Raman spectroscopy of blood plasma for cancer diagnosis", Proc. SPIE 12086, XV International Conference on Pulsed Lasers and Laser Applications, 120861M (2 December 2021); https://doi.org/10.1117/12.2613925

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