Measurement of emission spectra from the forearm by long-wave infrared passive spectroscopic imaging for non-invasive blood glucose sensors

Tomoya Kitazaki; Akira Nishiyama; Kenji Wada; Ichiro Ishimaru

doi:10.1117/12.2617369

31 May 2022 Measurement of emission spectra from the forearm by long-wave infrared passive spectroscopic imaging for non-invasive blood glucose sensors

Tomoya Kitazaki, Akira Nishiyama, Kenji Wada, Ichiro Ishimaru

Author Affiliations +

Proceedings Volume 12094, Algorithms, Technologies, and Applications for Multispectral and Hyperspectral Imaging XXVIII; 120940S (2022) https://doi.org/10.1117/12.2617369
Event: SPIE Defense + Commercial Sensing, 2022, Orlando, Florida, United States

Abstract

We intend to realize a non-invasive blood glucose sensor system based on long-wave infrared (LWIR) passive spectral imaging. We have developed an imaging-type two-dimensional Fourier transform spectrometer equipped with a microbolometer. Fourier transform spectroscopy is highly sensitive because of its high light-use efficiency. Our spectrometer is currently the only instrument capable of performing passive spectroscopic measurements at body temperature. The LWIR band is called the fingerprint region and is known to be highly suitable for component identification applications. In addition, LWIR radiation is emitted by the human body at room temperature, as can be observed in thermography. In active spectroscopy, light is used to illuminate the sample under test, and the amount of light absorbed as a result of molecular vibrations is measured. Therefore, in water-containing samples such as human skin, only the spectral characteristics near the skin surface can be observed because the absorption of the light by water is very strong. However, passive spectroscopy does not require illumination and thus can measure the amount of emitted light that arises from molecular vibrations. We therefore propose that it is possible to determine a subject’s blood glucose levels by measuring the radiation from the deep skin layer in which the blood vessels are located. In this report, we present passive spectroscopic measurements of a human forearm and report successful detection of the characteristic emission peak of glucose.

Conference Presentation

Citation Download Citation

Tomoya Kitazaki, Akira Nishiyama, Kenji Wada, and Ichiro Ishimaru "Measurement of emission spectra from the forearm by long-wave infrared passive spectroscopic imaging for non-invasive blood glucose sensors", Proc. SPIE 12094, Algorithms, Technologies, and Applications for Multispectral and Hyperspectral Imaging XXVIII, 120940S (31 May 2022); https://doi.org/10.1117/12.2617369

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available