Mueller-matrix microscopy of laser-induced monochromatic fluorescent fields of preparations of human internal organs and histological diagnostics of the time of age of damage formation

A. Yu. Litvinenko; D. Kvasnyuk; A. Ya. Vanchulyak; M. Stashkevich; A. V. Motrich; A. Yu Mikhailova; M. P. Gorskiy; M. M. Slyotov

doi:10.1117/12.2616667

20 December 2021 Mueller-matrix microscopy of laser-induced monochromatic fluorescent fields of preparations of human internal organs and histological diagnostics of the time of age of damage formation

A. Yu. Litvinenko, D. Kvasnyuk, A. Ya. Vanchulyak, M. Stashkevich, A. V. Motrich, A. Yu Mikhailova, M. P. Gorskiy, M. M. Slyotov

Author Affiliations +

Proceedings Volume 12126, Fifteenth International Conference on Correlation Optics; 1212623 (2021) https://doi.org/10.1117/12.2616667
Event: Fifteenth International Conference on Correlation Optics, 2021, Chernivtsi, Ukraine

Abstract

The article contains the results of experimental testing of methods of azimuthal-invariant Mueller-matrix microscopy (Mueller-matrix invariants - MMI) of optically anisotropic fluorophores of samples of histological sections of the brain, liver and kidney, as well as myocardium and lung tissue; temporal detection of variations in the magnitude of the statistical moments of the 1st - 4th orders, characterizing the distributions of the MMI value of linear birefringence and optical activity of samples of histological sections of the brain, liver and kidney, as well as myocardium and lung tissue with different age of damage; determination of the diagnostic efficiency (time interval and accuracy) of establishing the age of damage to human internal organs by digital histological methods of MMI mapping of optical anisotropy of fluorophores in histological sections of the brain, liver and kidney, as well as myocardium and lung tissue.

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A. Yu. Litvinenko, D. Kvasnyuk, A. Ya. Vanchulyak, M. Stashkevich, A. V. Motrich, A. Yu Mikhailova, M. P. Gorskiy, and M. M. Slyotov "Mueller-matrix microscopy of laser-induced monochromatic fluorescent fields of preparations of human internal organs and histological diagnostics of the time of age of damage formation", Proc. SPIE 12126, Fifteenth International Conference on Correlation Optics, 1212623 (20 December 2021); https://doi.org/10.1117/12.2616667

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