Picosecond laser irradiation by using micro-lens arrays and diffractive optical elements on different skin types

Hyeonsoo Kim; Jongman Choi; Hyun Wook Kang

doi:10.1117/12.2626644

11 January 2022 Picosecond laser irradiation by using micro-lens arrays and diffractive optical elements on different skin types

Hyeonsoo Kim, Jongman Choi, Hyun Wook Kang

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Proceedings Volume 12159, SPIE Advanced Biophotonics Conference (SPIE ABC 2021); 121590H (2022) https://doi.org/10.1117/12.2626644
Event: SPIE Advanced Biophotonics Conference (SPIE ABC 2021), 2021, Busan, Republic of Korea

Abstract

Melasma is caused by hyperpigmentation of the skin. The risk factors of melasma include ultra-violet light exposure, hormonal malfunction, and genetic predisposition. However, the precise risk factors of melasma is still unmapped. As melasma occurs regardless of regions and races, treatment planning should consider the optical characteristics of various skin colors to enhance clinical outcomes. The aim of the current study was to evaluate the laser-induced optical breakdown effects during picosecond laser irradiation with micro-lens arrays (MLA) and diffractive optical elements (DOE) on different colors of ex vivo porcine skin tissue. Two different radiant exposures (3.0 and 6.0 J/cm² ) were irradiated 20 times with a 50-μm lateral movement on the black and white skin tissue that matched with photo skin type Ⅵ and Ⅰ. In the black skin tissue, MLA and DOE yielded laser-induced vacuoles in dermis (vacuole depth = 283 ± 114 μm for MLA vs. 140 ± 62 μm for DOE; vacuole size = 67 ± 34 μm for MLA vs. 40 ± 21 μm for DOE). However, the white skin tissue displayed the deeper and larger vacuoles in the dermis (depth = 368 ± 171 μm and size = 134 ± 100 μm for MLA), compared to the black skin tissue. However, DOE generated photo-disruption in the dermis with no laser-induced vacuolization in the white skin tissue. In conclusion, the white skin could lead to deeper laser-induced vacuoles at larger sizes, compared to the black skin after the picosecond laser treatment with MLA and DOE.

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Hyeonsoo Kim, Jongman Choi, and Hyun Wook Kang "Picosecond laser irradiation by using micro-lens arrays and diffractive optical elements on different skin types", Proc. SPIE 12159, SPIE Advanced Biophotonics Conference (SPIE ABC 2021), 121590H (11 January 2022); https://doi.org/10.1117/12.2626644

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KEYWORDS

Skin

Diffractive optical elements

Laser tissue interaction

Picosecond phenomena

Tissue optics

Tissues

Laser optics

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