Dual modality handheld adaptive optics optical coherence tomography probe for in vivo 3-D photoreceptor imaging

Kristen Hagan; Jongwan Park; Theodore B. DuBose; Somayyeh Soltanian-Zadeh; Al-Hafeez Dhalla; Anthony N. Kuo; Ryan P. McNabb; Joseph A. Izatt; Sina Farsiu

doi:10.1117/12.2648479

14 March 2023 Dual modality handheld adaptive optics optical coherence tomography probe for in vivo 3-D photoreceptor imaging

Kristen Hagan, Jongwan Park, Theodore B. DuBose, Somayyeh Soltanian-Zadeh, Al-Hafeez Dhalla, Anthony N. Kuo, Ryan P. McNabb, Joseph A. Izatt, Sina Farsiu

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Proceedings Volume 12360, Ophthalmic Technologies XXXIII; 123600D (2023) https://doi.org/10.1117/12.2648479
Event: SPIE BiOS, 2023, San Francisco, California, United States

Abstract

Adaptive optics optical coherence tomography (AO-OCT) has allowed for the reliable 3-D imaging of individual retinal cells. The current AO-OCT systems are limited to tabletop implementation due to their size and complexity. This work describes the design and implementation of the first dual modality handheld AO-OCT (HAOOCT) and scanning laser ophthalmoscope (SLO) probe to extend AO-OCT imaging to previously excluded patients. Simultaneous SLO imaging allows for tracking of imaging features for HAOOCT localization. Pilot experiments on stabilized and recumbent adults using HAOOCT, weighing only 665 grams, revealed the 3-D photoreceptor structure for the first time using a handheld AO-OCT/SLO device.

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Kristen Hagan, Jongwan Park, Theodore B. DuBose, Somayyeh Soltanian-Zadeh, Al-Hafeez Dhalla, Anthony N. Kuo, Ryan P. McNabb, Joseph A. Izatt, and Sina Farsiu "Dual modality handheld adaptive optics optical coherence tomography probe for in vivo 3-D photoreceptor imaging", Proc. SPIE 12360, Ophthalmic Technologies XXXIII, 123600D (14 March 2023); https://doi.org/10.1117/12.2648479

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