Large area robotically assisted optical coherence tomography (LARA-OCT) for skin imaging with MHz-OCT surface tracking

Madita Göb; Simon Lotz; Linh Ha-Wissel; Sazgar Burhan; Sven Böttger; Floris Ernst; Jennifer Hundt; Robert Huber

doi:10.1117/12.2652616

8 March 2023 Large area robotically assisted optical coherence tomography (LARA-OCT) for skin imaging with MHz-OCT surface tracking

Madita Göb, Simon Lotz, Linh Ha-Wissel, Sazgar Burhan, Sven Böttger, Floris Ernst, Jennifer Hundt, Robert Huber

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Proceedings Volume 12367, Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XXVII; 123670C (2023) https://doi.org/10.1117/12.2652616
Event: SPIE BiOS, 2023, San Francisco, California, United States

Abstract

Optical coherence tomography (OCT) is a powerful imaging technique to non-invasively differentiate between healthy skin and pathological conditions. Unfortunately, commercially available OCT-systems are typically slow and not capable of scanning large areas at reasonable speed. Since skin lesions may extend over several square centimeters, potential inflammatory infiltrates remain undetected. Here, we present large area robotically assisted OCT (LARA-OCT) for skin imaging. Therefor a collaborative robot is combined with an existing, home-built 3.3 MHz-OCT-system and for surface tracking an online probe-to-surface control is implemented which is solely based on the OCT surface signal. It features a combined surface-distance and surface-orientation closed-loop control algorithm, which enables automatic positioning and alignment of the probe across the target while imaging. This allows to acquire coherent OCT images of skin areas beyond 10 cm².

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Madita Göb, Simon Lotz, Linh Ha-Wissel, Sazgar Burhan, Sven Böttger, Floris Ernst, Jennifer Hundt, and Robert Huber "Large area robotically assisted optical coherence tomography (LARA-OCT) for skin imaging with MHz-OCT surface tracking", Proc. SPIE 12367, Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XXVII, 123670C (8 March 2023); https://doi.org/10.1117/12.2652616

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KEYWORDS

Optical coherence tomography

Skin

Imaging systems

3D acquisition

3D image processing

Data acquisition

Optical tracking

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