Identification of precancer oral lesions using minimally invasive sampling techniques and Raman microspectroscopy

Isha Behl; Genecy Calado; Stephen Flint D.D.S.; Sheila Galvin; Claire Healy; Hugh J. Byrne; Fiona M. Lyng

doi:10.1117/12.2654997

6 March 2023 Identification of precancer oral lesions using minimally invasive sampling techniques and Raman microspectroscopy

Isha Behl, Genecy Calado, Stephen Flint D.D.S., Sheila Galvin, Claire Healy, Hugh J. Byrne, Fiona M. Lyng

Author Affiliations +

Proceedings Volume 12373, Optical Biopsy XXI: Toward Real-Time Spectroscopic Imaging and Diagnosis; 1237305 (2023) https://doi.org/10.1117/12.2654997
Event: SPIE BiOS, 2023, San Francisco, California, United States

Abstract

The gold standard diagnosis of oral pre-cancer/cancer is an invasive biopsy followed by a histological examination, which may present psychological trauma and risk of infection to patients. Moreover, multiple biopsies are often required to monitor precancer lesions' progression. With the aim of reducing the need for multiple biopsies, this study was undertaken to identify pre-cancerous lesions using minimally invasive brush biopsy and saliva samples, analysed by Raman spectroscopy.

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Citation Download Citation

Isha Behl, Genecy Calado, Stephen Flint D.D.S., Sheila Galvin, Claire Healy, Hugh J. Byrne, and Fiona M. Lyng "Identification of precancer oral lesions using minimally invasive sampling techniques and Raman microspectroscopy", Proc. SPIE 12373, Optical Biopsy XXI: Toward Real-Time Spectroscopic Imaging and Diagnosis, 1237305 (6 March 2023); https://doi.org/10.1117/12.2654997

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