Superconducting nanowire detector for interstitial null-separation time-domain diffuse optical spectroscopy

Vamshi Damagatla; Pranav Lanka; Andrea Farina; Annalisa Brodu; Niels Noordzijc; Jessie Qin-Dregely; Antonio Pifferi

doi:10.1117/12.2649028

7 March 2023 Superconducting nanowire detector for interstitial null-separation time-domain diffuse optical spectroscopy

Vamshi Damagatla, Pranav Lanka, Andrea Farina, Annalisa Brodu, Niels Noordzijc, Jessie Qin-Dregely, Antonio Pifferi

Author Affiliations +

Proceedings Volume 12376, Optical Tomography and Spectroscopy of Tissue XV; 123760F (2023) https://doi.org/10.1117/12.2649028
Event: SPIE BiOS, 2023, San Francisco, California, United States

Abstract

We demonstrate a novel realization of Interstitial fiber, broadband, Time Domain Diffuse Optical Spectroscopy (TD-DOS) in Null Source-Detector separation (NSDS) approach without temporal gating, by using a Super-conducting Nanowire single photon detector (SNSPD) for acquisition. We test its feasibility by performing Monte Carlo simulations and comparing the absorption retrieval of the SNSPD with an ideal scenario and a standard Silicon Photomultiplier (SiPM). Consequently, as per the MEDPHOT protocol, we test experimentally, the absorption linearity of the system on tissue-equivalent liquid phantoms and demonstrate the scattering independent retrieval of the absorption spectrum of water using Intralipid phantoms in the wavelength range of 600-1100 nm.

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Citation Download Citation

Vamshi Damagatla, Pranav Lanka, Andrea Farina, Annalisa Brodu, Niels Noordzijc, Jessie Qin-Dregely, and Antonio Pifferi "Superconducting nanowire detector for interstitial null-separation time-domain diffuse optical spectroscopy", Proc. SPIE 12376, Optical Tomography and Spectroscopy of Tissue XV, 123760F (7 March 2023); https://doi.org/10.1117/12.2649028

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