A Stokes imaging microscope system with a large field of view

Huibin Yang; Jiawei Song; Nan Zeng; Hui Ma

doi:10.1117/12.2648887

15 March 2023 A Stokes imaging microscope system with a large field of view

Huibin Yang, Jiawei Song, Nan Zeng, Hui Ma

Author Affiliations +

Proceedings Volume 12382, Polarized Light and Optical Angular Momentum for Biomedical Diagnostics 2023; 1238209 (2023) https://doi.org/10.1117/12.2648887
Event: SPIE BiOS, 2023, San Francisco, California, United States

Conference Poster

Abstract

In this paper, we have built a Stokes imaging microscope system with a large field of view, and then validated the system. Because of the thin pathology sections and the low signal-to-noise ratio of Stokes imaging, accurate measurements of the weaker polarization signals are required. So at the light source side, we added a beam shaping module to make the distribution of light intensity more uniform. In addition, we used air as a standard sample to calibrate the measurement results, which makes the results more accurate. The specific slide scanning process is also presented in this paper, and we have used the solution to test it on actual pathology sections, and the experimental results show that the complete system works well and has the potential to assist in pathology analysis.

Citation Download Citation

Huibin Yang, Jiawei Song, Nan Zeng, and Hui Ma "A Stokes imaging microscope system with a large field of view", Proc. SPIE 12382, Polarized Light and Optical Angular Momentum for Biomedical Diagnostics 2023, 1238209 (15 March 2023); https://doi.org/10.1117/12.2648887

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