Ventricular tachycardia (VT) can be treated with catheter ablation therapy, a technique in which catheters are guided into the ventricle and radiofrequency energy is delivered into the myocardial tissue to stop arrhythmic electrical pathways. These procedures are invasive and come with associated risks; therefore, recent efforts have investigated the use of noninvasive proton beam therapy for treatment of VT. In this approach, target regions are identified in a pre-treatment computed tomography scan of the left ventricle followed by proton beam ablation therapy. The effects of beam ablation therapy in myocardial tissue can be characterized using imaging, electroanatomic mapping, and histology. These data are also important for determining the appropriate dose for effective treatment of VT while minimizing collateral damage to surrounding healthy tissue. Studies conducted to date demonstrate that proton beam ablation is a promising new approach for treatment of VT.
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