Evaluation of a CdTe photon-counting detector in medical imaging: performance metrics and distortion correction approaches

Harsha Marupudi; Joseph A. Manus; Muhammad U. Ghani; Andrey Makeev; Stephen J. Glick; Bahaa Ghammraoui

doi:10.1117/12.3008625

3 April 2024 Evaluation of a CdTe photon-counting detector in medical imaging: performance metrics and distortion correction approaches

Harsha Marupudi, Joseph A. Manus, Muhammad U. Ghani, Andrey Makeev, Stephen J. Glick, Bahaa Ghammraoui

Author Affiliations +

Proceedings Volume 12925, Medical Imaging 2024: Physics of Medical Imaging; 129252Z (2024) https://doi.org/10.1117/12.3008625
Event: SPIE Medical Imaging, 2024, San Diego, California, United States

Conference Poster

Abstract

This study assesses the impact of charge summing correction (CSC) on a Cadmium Telluride (CdTe) Photon Counting Detector in breast CT. A laboratory benchtop system that consists of a 0.1 mm pixel pitch CdTe detector and a tungsten anode X-ray source. Images were acquired at 55 kVp with 2 mm Al external filtration under three different tube currents of 25, 100, and 200 mA at high and low energy thresholds. Performance was evaluated using contrast to noise ratio (CNR), modulation transfer function (MTF), noise power spectrum (NPS), and iodine quantification. Anticoincidence (AC) and single pixel (SP) modes were compared, both with signal-to-thickness calibration and FDK reconstruction. AC mode displayed enhanced low-energy contrast and accurate iodine quantification, while SP mode had better CNR at low-energy. High fluence reduced AC mode uniformity, but not SP. Results indicate that CSC in breast CT improves iodine quantification but with the tradeoff of increased noise in low-energy images. These effects are dependent on the studied system and operational parameters.

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Harsha Marupudi, Joseph A. Manus, Muhammad U. Ghani, Andrey Makeev, Stephen J. Glick, and Bahaa Ghammraoui "Evaluation of a CdTe photon-counting detector in medical imaging: performance metrics and distortion correction approaches", Proc. SPIE 12925, Medical Imaging 2024: Physics of Medical Imaging, 129252Z (3 April 2024); https://doi.org/10.1117/12.3008625

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