Vascular imaging of in vivo human skin using a fiber-based PS-OCT system

Guoqiang Chen; Jipeng Ding; Wen'ai Wang; Yanqiu Li

doi:10.1117/12.3003964

24 November 2023 Vascular imaging of in vivo human skin using a fiber-based PS-OCT system

Guoqiang Chen, Jipeng Ding, Wen'ai Wang, Yanqiu Li

Proceedings Volume 12935, Fourteenth International Conference on Information Optics and Photonics (CIOP 2023); 129350L (2023) https://doi.org/10.1117/12.3003964
Event: Fourteenth International Conference on Information Optics and Photonics (CIOP 2023), 2023, Xi’an, China

Abstract

The detection and imaging of the microvascular map play a vital role in providing valuable pathological evidence for a variety of physiological disorders. Optical coherence tomography angiography (OCTA) is a non-invasive technique that allows high-speed, high-resolution visualization of microvascular networks without the need for contrast agents and invasive manipulation. In this study, we developed a fiber-based polarization-sensitive optical coherence tomography (PS-OCT) system that utilizes a 200 kHz swept source at 1310 nm. To reduce phase artifacts and provide excellent motion contrast for vascular imaging, we have incorporated the complex correlated phase gradient variance (CCPGV) method. Additionally, to address the challenges posed by birefringence dispersion, we implemented a dual-state numerical dispersion compensation method. By imaging human skin, we have successfully demonstrated the effectiveness of our system in visualizing the vascular map while minimizing noise interference. The high-quality imaging and accurate visualization of vascular networks provided by our system hold significant potential in enhancing the understanding and assessment of various pathological conditions. This can benefit both researchers and clinicians in their biomedical investigations and patient care.

(2023) Published by SPIE. Downloading of the abstract is permitted for personal use only.

Citation Download Citation

Guoqiang Chen, Jipeng Ding, Wen'ai Wang, and Yanqiu Li "Vascular imaging of in vivo human skin using a fiber-based PS-OCT system", Proc. SPIE 12935, Fourteenth International Conference on Information Optics and Photonics (CIOP 2023), 129350L (24 November 2023); https://doi.org/10.1117/12.3003964

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KEYWORDS

Imaging systems

Polarization

Skin

Visualization

Biological samples

Optical coherence tomography

Signal detection

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