Towards real-time hyperspectral imaging in neurosurgery

Alfie Roddan; Ziyan Yu; Maria Leiloglou; Vadzim Chalau; Giulio Anichini; Stamatia Giannarou; Daniel Elson

doi:10.1117/12.3017079

18 June 2024 Towards real-time hyperspectral imaging in neurosurgery

Alfie Roddan, Ziyan Yu, Maria Leiloglou, Vadzim Chalau, Giulio Anichini, Stamatia Giannarou, Daniel Elson

Author Affiliations +

Proceedings Volume 13009, Clinical Biophotonics III; 130090G (2024) https://doi.org/10.1117/12.3017079
Event: SPIE Photonics Europe, 2024, Strasbourg, France

Conference Poster

Abstract

This study aims to integrate real-time hyperspectral (HS) imaging with a surgical microscope to assist neurosurgeons in differentiating between healthy and pathological tissue during procedures. Using the LEICA M525 microscope’s optical ports, we register HS data and RGB, in an efforts to improve margin delineation and surgical outcomes. The CUBERT ULTRIS SR5 camera with 51 bands and 15 Hz is employed, and critical calibration steps are outlined for clinical application. Experimental validation is conducted on ex-vivo animal tissue using reflectance spectroscopy. We present the preliminary validation results of the performance comparison between the designed hyperspectral imaging microscope prototype and diffuse reflectance spectroscopy conducted on animal tissue.

(2024) Published by SPIE. Downloading of the abstract is permitted for personal use only.

Citation Download Citation

Alfie Roddan, Ziyan Yu, Maria Leiloglou, Vadzim Chalau, Giulio Anichini, Stamatia Giannarou, and Daniel Elson "Towards real-time hyperspectral imaging in neurosurgery", Proc. SPIE 13009, Clinical Biophotonics III, 130090G (18 June 2024); https://doi.org/10.1117/12.3017079

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