Monitoring of microvascular calcification by time-resolved photoacoustic microscopy

Yinshi Yu; Yahui Zhu; Chao Zuo; Haigang Ma

doi:10.1117/12.3036394

23 November 2024 Monitoring of microvascular calcification by time-resolved photoacoustic microscopy

Yinshi Yu, Yahui Zhu, Chao Zuo, Haigang Ma

Proceedings Volume 13238, Advanced Optical Imaging Technologies VII; 132380T (2024) https://doi.org/10.1117/12.3036394
Event: SPIE/COS Photonics Asia, 2024, Nantong, Jiangsu, China

Conference Poster

Abstract

Vascular calcification is a severe disease caused by dysregulated calcium-phosphate metabolism, influenced by factors such as genetics, aging, and chronic diseases, severely impacting vascular function. Vascular calcification inevitably leads to changes in vascular elasticity, which can be clearly reflected through elastography. However, existing elastography methods lack the resolution and sensitivity required for early-stage monitoring of vascular calcification. Thus, we propose a photoacoustic elastography method that combines optical and ultrasonic advantages, analyzing photoacoustic signals to obtain vascular elastic modulus and visualize calcification. This technology enables early detection of vascular calcification, providing crucial information for preventive and therapeutic strategies to reduce disease risk.

Citation Download Citation

Yinshi Yu, Yahui Zhu, Chao Zuo, and Haigang Ma "Monitoring of microvascular calcification by time-resolved photoacoustic microscopy", Proc. SPIE 13238, Advanced Optical Imaging Technologies VII, 132380T (23 November 2024); https://doi.org/10.1117/12.3036394

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