Effects of pressure rise on cw laser ablation of tissue

Gerald L. LeCarpentier; Massoud Motamedi; Ashley J. Welch

doi:10.1117/12.44112

1 June 1991 Effects of pressure rise on cw laser ablation of tissue

Gerald L. LeCarpentier, Massoud Motamedi, Ashley J. Welch

Proceedings Volume 1427, Laser-Tissue Interaction II; (1991) https://doi.org/10.1117/12.44112
Event: Optics, Electro-Optics, and Laser Applications in Science and Engineering, 1991, Los Angeles, CA, United States

Abstract

The objectives of this research were to identify mechanisms responsible for the initiation of continuous wave (cw) laser ablation of tissue and investigate the role of pressure in the ablation process. Porcine aorta samples were irradiated in a chamber pressurized from 1 X 10^-4 to 12 atmospheres absolute pressure. Acrylic and Zn-Se windows in the experimental pressure chamber allowed video and infrared cameras to simultaneously record mechanical and thermal events associated with cw argon laser ablation of these samples. Video and thermal images of tissue slabs documented the explosive nature of cw laser ablation of soft biological media and revealed similar ablation threshold temperatures and ablation onset times under different environmental pressures; however, more violent initiation explosions with decreasing environmental pressures were observed. These results suggest that ablation initiates with thermal alterations in the mechanical strength of the tissue and proceeds with an explosion induced by the presence superheated liquid within the tissue.

Citation Download Citation

Gerald L. LeCarpentier, Massoud Motamedi, and Ashley J. Welch "Effects of pressure rise on cw laser ablation of tissue", Proc. SPIE 1427, Laser-Tissue Interaction II, (1 June 1991); https://doi.org/10.1117/12.44112

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