Laser-assisted solder closure of bronchial stumps

Mehmet Cengiz Oz M.D.; Matthew R. Williams; Richard D. Moscarelli; Murat Kaynar; Christian I. Fras; Steven K. Libutti M.D.; Hillary Smith; Adrianne J. Setton; Michael R. Treat M.D.; Roman Nowygrod M.D.

doi:10.1117/12.137341

1 June 1992 Laser-assisted solder closure of bronchial stumps

Mehmet Cengiz Oz M.D., Matthew R. Williams, Richard D. Moscarelli, Murat Kaynar, Christian I. Fras, Steven K. Libutti M.D., Hillary Smith, Adrianne J. Setton, Michael R. Treat M.D., Roman Nowygrod M.D.

Author Affiliations +

Proceedings Volume 1643, Laser Surgery: Advanced Characterization, Therapeutics, and Systems III; (1992) https://doi.org/10.1117/12.137341
Event: OE/LASE '92, 1992, Los Angeles, CA, United States

Abstract

Broncho-pleural fistula is a difficult clinical problem without a simple solution. Laser-assisted solder techniques potentially offer a means to precisely fix tissue glues into the fistulae through a bronchoscopic approach. Using a canine model, secondary bronchi were sealed with cryoprecipitate made from solvent/detergent treated plasma (treated to inactivate membrane enveloped virus) mixed with indocyanine green (absorption 805 nm). Diode laser energy (emission 808 nm, 7.3 W/cm²) was applied to the solder until desiccation was observed. Leakage pressures ranged between 18 - 86 mmHg with a mean of 46 +/- 24 mmHg. Laser-assisted solder techniques provide a reliably strong seal over leaking bronchial stumps and use of dye enhancement prevents undesired collateral thermal injury to surrounding bronchial tissue. Solvent/detergent plasma, prepared by methods shown to inactivate large quantities of HIV, HBV, and HCV, is an effective source of cyroprecipitate and should allow widespread use of pooled human material in a clinical setting.

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Mehmet Cengiz Oz M.D., Matthew R. Williams, Richard D. Moscarelli, Murat Kaynar, Christian I. Fras, Steven K. Libutti M.D., Hillary Smith, Adrianne J. Setton, Michael R. Treat M.D., and Roman Nowygrod M.D. "Laser-assisted solder closure of bronchial stumps", Proc. SPIE 1643, Laser Surgery: Advanced Characterization, Therapeutics, and Systems III, (1 June 1992); https://doi.org/10.1117/12.137341

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