Exposure to propylene- and diethylene glycol ethers: analytical methods and biological monitoring

Bernd Huebner; Karl Heinz Schaller; Juergen Angerer

doi:10.1117/12.140260

9 March 1993 Exposure to propylene- and diethylene glycol ethers: analytical methods and biological monitoring

Bernd Huebner, Karl Heinz Schaller, Juergen Angerer

Proceedings Volume 1716, International Conference on Monitoring of Toxic Chemicals and Biomarkers; (1993) https://doi.org/10.1117/12.140260
Event: Environmental Sensing '92, 1992, Berlin, Germany

Abstract

Twenty-two people involved with manufacturing brakehoses and exposed to the glycol ether 1- methoxypropanol-2, were assessed according to the external and internal exposure to this solvent. The elimination kinetics of 1-methoxypropanol-2 in man were studied and mean excretion half lives of approximately 4.4 h were found. On the basis of our results, we made a rough calculation for a future biological tolerance value for 1-methoxypropanol-2. On that basis we would expect that concentrations from 38 to 109 mg per liter of blood and 10 to 31 mg per liter of urine would correspond to the German maximum concentration at the workplace for 1-methoxypropanol-2 of 375 mg/m³. In addition, the analytical method which has been used for this purpose and its reliability criteria are shown.

Citation Download Citation

Bernd Huebner, Karl Heinz Schaller, and Juergen Angerer "Exposure to propylene- and diethylene glycol ethers: analytical methods and biological monitoring", Proc. SPIE 1716, International Conference on Monitoring of Toxic Chemicals and Biomarkers, (9 March 1993); https://doi.org/10.1117/12.140260

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