Focused neutron beam dose deposition profiles in tissue equivalent materials: a pilot study for BNCT

Rulon R. Mayer; James Welsh; Huaiyu Heather Chen-Mayer

doi:10.1117/12.267874

27 February 1997 Focused neutron beam dose deposition profiles in tissue equivalent materials: a pilot study for BNCT

Rulon R. Mayer, James Welsh, Huaiyu Heather Chen-Mayer

Proceedings Volume 2867, International Conference Neutrons in Research and Industry; (1997) https://doi.org/10.1117/12.267874
Event: Fifth International Conference on Applications of Nuclear Techniques: Neutrons in Research and Industry, 1996, Crete, Greece

Abstract

Boron Neutron Capture Therapy (BNCT) has been limited by the inability to direct neutrons toward the therapeutic target and away from sensitive normal tissues. The recently developed Kumakhov lens has focused a broad incident low energy neutron beam in air to a sub-mm spot. This study examines the radiation does distribution of a converging beam passing through tissue equivalent materials. A neutron beam exiting a focusing lens is directed toward a stack of thin radiochromic media sandwiched between plastic sheets. The depth dose and beam profile within the tissue equivalent materials are determined by optical scanning and image processing of the individual radiochromic media sheets, a polymer based dosimetry medium which darkens upon exposure to ionizing radiation. The alpha particle emission from boron is examined by substituting a plastic sheet with a ⁶Li enriched lithium carbonate sheet positioned at the focal plane. The information will help determine the feasibility of applying the focused neutron beam to BNCT for therapy.

Citation Download Citation

Rulon R. Mayer, James Welsh, and Huaiyu Heather Chen-Mayer "Focused neutron beam dose deposition profiles in tissue equivalent materials: a pilot study for BNCT", Proc. SPIE 2867, International Conference Neutrons in Research and Industry, (27 February 1997); https://doi.org/10.1117/12.267874

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