Bile sensing with optical fibers

Francesco Baldini; Paolo Bechi; Fabio Cianchi; Roberta Coppini; Alida Falai

doi:10.1117/12.336925

15 January 1999 Bile sensing with optical fibers

Francesco Baldini, Paolo Bechi, Fabio Cianchi, Roberta Coppini, Alida Falai

Proceedings Volume 3570, Biomedical Sensors, Fibers, and Optical Delivery Systems; (1999) https://doi.org/10.1117/12.336925
Event: BiOS Europe '98, 1998, Stockholm, Sweden

Abstract

Bile determination is very useful to diagnose many gastric pathologies. Actually, the measurement is performed with Bilitec 2000, an optical fiber sensor, based on the absorption of bilirubin. Nevertheless, erroneous evaluations can occur due to different configurations which the bilirubin molecule can adopt. The optical behavior of human samples of pure bile and bile + gastric juice has been examined by an optical fiber spectrophotometer and two properly modified Bilitec 2000 units. Analysis of pH dependance evidenced the presence of different calibration curves at different pH values, which Bilitec units showed that 420 nm could be a more appropriate wavelength for bilirubin detection.

Citation Download Citation

Francesco Baldini, Paolo Bechi, Fabio Cianchi, Roberta Coppini, and Alida Falai "Bile sensing with optical fibers", Proc. SPIE 3570, Biomedical Sensors, Fibers, and Optical Delivery Systems, (15 January 1999); https://doi.org/10.1117/12.336925

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