Microwave antenna array for prostrate hyperthermia

B. Stuart Trembly; P. Jack Hoopes D.V.M.; Karen L. Moodie; Arik S. Dvinsky

doi:10.1117/12.348746

19 May 1999 Microwave antenna array for prostrate hyperthermia

B. Stuart Trembly, P. Jack Hoopes D.V.M., Karen L. Moodie, Arik S. Dvinsky

Proceedings Volume 3594, Thermal Treatment of Tissue with Image Guidance; (1999) https://doi.org/10.1117/12.348746
Event: BiOS '99 International Biomedical Optics Symposium, 1999, San Jose, CA, United States

Abstract

A pair of microwave applicators was developed to produce controlled elevation of temperature in the prostate. One applicator was designed for placement in the urethra; it has a diameter of 6 mm and is flexible. This applicator incorporates a choked, resonant microwave dipole with an omnidirectional heating pattern and an air cooling system to control the temperature of the urothelium. The second applicator was designed for placement in the rectum; it has a diameter of 18 mm and is rigid. It incorporates an eccentric, choked, resonant microwave dipole that radiates toward the prostate with a front-to-back power ratio of about twenty. An air cooling system controls the temperature of the rectal mucosa. The applicators are driven at 915 MHz with a phase difference chosen to produce the maximum temperature in the central prostate. We heated the prostates of eight canine subjects with the transurethral and transrectal applicators. After one or two months of followup in four subjects, the prostates and surrounding tissues were evaluated histologically. We present experimental measurements of the power deposition patterns of the applicators and the 3D temperature distributions in vivo, and we correlate the thermal dose with histopathological observations.

Citation Download Citation

B. Stuart Trembly, P. Jack Hoopes D.V.M., Karen L. Moodie, and Arik S. Dvinsky "Microwave antenna array for prostrate hyperthermia", Proc. SPIE 3594, Thermal Treatment of Tissue with Image Guidance, (19 May 1999); https://doi.org/10.1117/12.348746

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