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In this paper, the roles that the light of PDT plays were classified into two kinds, PDT1 and PDT2. PDT1 is mediated by photosensitizer. PDT2 results from the direct interaction of light with target cells. As only the photosensitizers in the membrane of a cell can be in the coherent state, PDT1 is mediated by the coherent interaction of membrane photosensitizers, and its main target is the membranes of a cell. PDT2 is governed by the biological information model of low intensity laser (BIML) put forward by Liu TCY et al. According to BIML under the dose of PDT, cold-color (green, blue or violet) laser irradiation activates adenylate cyclase through Gs protein: cAMP$ARUP; hot color (red, orange or yellow) laser irradiation activates cAMP phosphodiesterase through Gi protein or activates phosphoinositide phospholipase C through Gq protein or activates one of receptor-linked enzyme: cAMP$ARDN. After reviewing simply the PDT effects on cells from the viewpoint of information biology and the research on them by use of optical spectroscopic approach, we arrived at the conclusion that cold color light PDT is better than hot color light PDT from the viewpoint of the effects on cell and the short term effects on cancer, but hot color light PDT is superior to cold color light PDT with respect to the long term effects on cancer.
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