Progress in development of an imaging system for fluorescence detection of GI tract cancers

Jacqueline Hewett; Tracy McKechnie; Wilson Sibbett; Iain Tait; Sami Mohammed; Alfred Cushieri; Valerie Nadeau; Miles J. Padgett

doi:10.1117/12.379886

29 March 2000 Progress in development of an imaging system for fluorescence detection of GI tract cancers

Jacqueline Hewett, Tracy McKechnie, Wilson Sibbett, Iain Tait, Sami Mohammed, Alfred Cushieri, Valerie Nadeau, Miles J. Padgett

Author Affiliations +

Proceedings Volume 3909, Optical Methods for Tumor Treatment and Detection: Mechanisms and Techniques in Photodynamic Therapy IX; (2000) https://doi.org/10.1117/12.379886
Event: BiOS 2000 The International Symposium on Biomedical Optics, 2000, San Jose, CA, United States

Abstract

We report on the development of a fluorescence imaging system for early detection of cancers in the GI tract. The system comprises a modified light source, endoscope, camera and associated image processing software. The photosensitizing agent is 5-aminolaevulinic acid, metabolized within the tumor to form protoporphyrin IX that absorbs strongly between 390-410 nm and fluoresces at 635 nm.

Citation Download Citation

Jacqueline Hewett, Tracy McKechnie, Wilson Sibbett, Iain Tait, Sami Mohammed, Alfred Cushieri, Valerie Nadeau, and Miles J. Padgett "Progress in development of an imaging system for fluorescence detection of GI tract cancers", Proc. SPIE 3909, Optical Methods for Tumor Treatment and Detection: Mechanisms and Techniques in Photodynamic Therapy IX, (29 March 2000); https://doi.org/10.1117/12.379886

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