Polarized light propagation through tissue and tissue phantoms

Vanitha Sankaran M.D.; Joseph T. Walsh Jr.; Duncan J. Maitland

doi:10.1117/12.384154

28 April 2000 Polarized light propagation through tissue and tissue phantoms

Vanitha Sankaran M.D., Joseph T. Walsh Jr., Duncan J. Maitland

Proceedings Volume 3915, Coherence Domain Optical Methods in Biomedical Science and Clinical Applications IV; (2000) https://doi.org/10.1117/12.384154
Event: BiOS 2000 The International Symposium on Biomedical Optics, 2000, San Jose, CA, United States

Abstract

We show that standard tissue phantoms can be sued to mimic the intensity and polarization properties of tissue. Polarized light propagation through biologic tissue is typically studied using tissue phantoms consisting of dilute aqueous suspensions of microspheres. The dilute phantoms can empirically match tissue polarization and intensity properties. One discrepancy between the dilute phantoms and tissue exist: common tissue phantoms, such as dilute Intralipid and dilute 1-micrometers -diameter polystyrene microsphere suspension, depolarize linearly polarized light more quickly than circular polarized light. In dense tissue, however, where scatterers are often locate din close proximity to one another, circularly polarized light is depolarized similar to more quickly than linearly polarized light. We also demonstrate that polarized light is depolarized similar to or more quickly than linearly polarized light. We also demonstrate that polarized light propagates differently in dilute versus densely packed microsphere suspensions, which may account for the differences seen between polarized light propagation in common dilute tissue phantoms versus dense biologic tissue.

Citation Download Citation

Vanitha Sankaran M.D., Joseph T. Walsh Jr., and Duncan J. Maitland "Polarized light propagation through tissue and tissue phantoms", Proc. SPIE 3915, Coherence Domain Optical Methods in Biomedical Science and Clinical Applications IV, (28 April 2000); https://doi.org/10.1117/12.384154

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available

Members: $17.00

Non-members: $21.00 ADD TO CART

PROCEEDINGS
9 PAGES

DOWNLOAD PAPER SAVE TO MY LIBRARY

GET CITATION

RIGHTS & PERMISSIONS

Get copyright permission Get copyright permission on Copyright Marketplace

KEYWORDS

Tissues

Polarization

Tissue optics

Optical spheres

Scattering

Mie scattering

Blood

Show All Keywords

Keywords/Phrases

Search In:

Publication Years