Computerized image analysis: estimation of breast density on mammograms

Chuan Zhou; Heang-Ping Chan; Nicholas Petrick; Berkman Sahiner; Mark A. Helvie M.D.; Marilyn A. Roubidoux; Lubomir M. Hadjiiski; Mitchell M. Goodsitt

doi:10.1117/12.387676

6 June 2000 Computerized image analysis: estimation of breast density on mammograms

Chuan Zhou, Heang-Ping Chan, Nicholas Petrick, Berkman Sahiner, Mark A. Helvie M.D., Marilyn A. Roubidoux, Lubomir M. Hadjiiski, Mitchell M. Goodsitt

Author Affiliations +

Proceedings Volume 3979, Medical Imaging 2000: Image Processing; (2000) https://doi.org/10.1117/12.387676
Event: Medical Imaging 2000, 2000, San Diego, CA, United States

Abstract

An automated image analysis tool is being developed for estimation of mammographic breast density, which may be useful for risk estimation or for monitoring breast density change in a prevention or intervention program. A mammogram is digitized using a laser scanner and the resolution is reduced to a pixel size of 0.8 mm X 0.8 mm. Breast density analysis is performed in three stages. First, the breast region is segmented from the surrounding background by an automated breast boundary-tracking algorithm. Second, an adaptive dynamic range compression technique is applied to the breast image to reduce the range of the gray level distribution in the low frequency background and to enhance the differences in the characteristic features of the gray level histogram for breasts of different densities. Third, rule-based classification is used to classify the breast images into several classes according to the characteristic features of their gray level histogram. For each image, a gray level threshold is automatically determined to segment the dense tissue from the breast region. The area of segmented dense tissue as a percentage of the breast area is then estimated. In this preliminary study, we analyzed the interobserver variation of breast density estimation by two experienced radiologists using BI-RADS lexicon. The radiologists' visually estimated percent breast densities were compared with the computer's calculation. The results demonstrate the feasibility of estimating mammographic breast density using computer vision techniques and its potential to improve the accuracy and reproducibility in comparison with the subjective visual assessment by radiologists.

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Chuan Zhou, Heang-Ping Chan, Nicholas Petrick, Berkman Sahiner, Mark A. Helvie M.D., Marilyn A. Roubidoux, Lubomir M. Hadjiiski, and Mitchell M. Goodsitt "Computerized image analysis: estimation of breast density on mammograms", Proc. SPIE 3979, Medical Imaging 2000: Image Processing, (6 June 2000); https://doi.org/10.1117/12.387676

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