CONFERENCE PROCEEDINGS
Advanced Search
Home > Proceedings > Volume 4250 > Article
Open Access Paper
29 June 2001 Broadband absorption spectroscopy by combining frequency-domain and steady-state techniques
Andrew J. Berger, Frederic Bevilacqua, Dorota B. Jakubowski, Albert E. Cerussi, John A. Butler, D. Hsiang, Bruce J. Tromberg
Author Affiliations +
Proceedings Volume 4250, Optical Tomography and Spectroscopy of Tissue IV; (2001) https://doi.org/10.1117/12.434510
Event: BiOS 2001 The International Symposium on Biomedical Optics, 2001, San Jose, CA, United States
Abstract
A technique for measuring broadband near-infrared absorption spectra of turbid media is presented using a combination of frequency-domain (FD) and steady-state (SS) reflectance methods. Most of the wavelength coverage is provided by a white-light SS measurement, while the FD data are acquired at a few selected wavelengths. Coefficients of absorption ((mu) a) and reduced scattering ((mu) s') derived from the FD data are used to intensity-calibrate the SS measurements and to estimate (mu) s' at all wavelengths in the spectral window of interest. After these steps are performed, (mu) a can be determined by comparing the SS reflectance values to the predictions of diffusion theory, wavelength by wavelength. We present an application of this method to breast tumor characterization. A case study of a fibroadenoma is shown, where different absorption spectra were found between the normal and the tumor sides.
© (2001) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
Citation Download Citation
Andrew J. Berger, Frederic Bevilacqua, Dorota B. Jakubowski, Albert E. Cerussi, John A. Butler, D. Hsiang, and Bruce J. Tromberg "Broadband absorption spectroscopy by combining frequency-domain and steady-state techniques", Proc. SPIE 4250, Optical Tomography and Spectroscopy of Tissue IV, (29 June 2001); https://doi.org/10.1117/12.434510
PROCEEDINGS
 6 PAGES
DOWNLOAD PAPER SAVE TO MY LIBRARY
GET CITATION
Lens.org Logo
CITATIONS
Cited by 1 scholarly publication.
Advertisement
Advertisement
RIGHTS & PERMISSIONS
Get copyright permission  Get copyright permission on Copyright Marketplace
KEYWORDS
Reflectivity
Absorption
Breast
Tumors
Optical fibers
Scattering
Tissues
RELATED CONTENT
Subscribe to Digital Library
Receive Erratum Email Alert
Back to Top