Sampling volume produced by shallow optical probes in skin reflectance measurements

Igor Victorovich Meglinski; Stephen John Matcher

doi:10.1117/12.438426

22 August 2001 Sampling volume produced by shallow optical probes in skin reflectance measurements

Igor Victorovich Meglinski, Stephen John Matcher

Proceedings Volume 4427, Imaging of Tissue Structure and Function; (2001) https://doi.org/10.1117/12.438426
Event: Imaging of Tissue Structure and Function, 2001, none, Russian Federation

Abstract

The absolute quantified measurement of hemoglobin skin blood saturation from collected reflectance spectra of the skin is complicated by the fact that the blood content of tissues can vary both in the spatial distribution and in the amount. These measurements require an understanding of which vascular bed is primarily responsible for the detected signal. Knowing the spatial detector depth sensitivity makes it possible to find the best range of different probe geometries for the measurements of signal from the required zones and group of vessels inside the skin. To facilitate this we have developed a Monte Carlo simulation to estimate the sampling volume offered by fiber-optic probes with a small source detector spacing, and by the confocal probe. The optical properties of the modeled medium were taken to be optical properties of the Caucasian type of skin tissues in the visible range of the spectrum. The authors propose this simple numerical methods as a tool for the probes examination to yield measurements which are preferentially sensitive to blood at different depths within the skin.

Citation Download Citation

Igor Victorovich Meglinski and Stephen John Matcher "Sampling volume produced by shallow optical probes in skin reflectance measurements", Proc. SPIE 4427, Imaging of Tissue Structure and Function, (22 August 2001); https://doi.org/10.1117/12.438426

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