Hybrid point-and-intensity-based deformable registration for abdominal CT images

Jay B. West; Calvin R. Maurer Jr.; John R. Dooley

doi:10.1117/12.595442

29 April 2005 Hybrid point-and-intensity-based deformable registration for abdominal CT images

Jay B. West, Calvin R. Maurer Jr., John R. Dooley

Proceedings Volume 5747, Medical Imaging 2005: Image Processing; (2005) https://doi.org/10.1117/12.595442
Event: Medical Imaging, 2005, San Diego, California, United States

Abstract

In this paper, we examine the problem of non-rigid, image-to-image registration for CT images of the abdomen. This problem has been previously addressed in many different contexts (e.g., visualization using different imaging modalities, modelling of organ deformation after surgical resection). The particular application in which we are interested is modelling of respiratory motion of abdominal organs, so that we may achieve a more accurate representation of the dose distribution in both targeted structures and non-targeted areas during radiosurgical treatment. Our goal is to register two CT images, each acquired at different positions in the respiratory cycle. We use a transformation model based on B-splines, and take advantage of B-splines' "locality" or "compact support" property to ensure computational efficiency and robust convergence to a satisfactory result. We demonstrate that, although a purely intensity-based registration metric performs well in matching the deformation of the lungs during the respiratory cycle, the movement of other organs (e.g., liver and kidney) is poorly represented due to the poor contrast within and between these organs in the CT images. We introduce a registration metric that is a weighted combination of intensity difference and distance between corresponding points that are manually identified in the two images being registered; we show how the influence of these points can be elegantly added to the metric so that it remains differentiable with respect to the spline control points. Visual inspection reveals that resulting registrations appear to be superior to the intensity-only ones in terms of representation of visceral organ deformation and movement.

Citation Download Citation

Jay B. West, Calvin R. Maurer Jr., and John R. Dooley "Hybrid point-and-intensity-based deformable registration for abdominal CT images", Proc. SPIE 5747, Medical Imaging 2005: Image Processing, (29 April 2005); https://doi.org/10.1117/12.595442

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available