Fluorescent and photodynamic properties of near-infrared photosensitizer bacteriochlorophyllide-serine

I. G. Meerovich; I. Yu. Kubasova; N. A. Oborotova; G. A. Meerovich; S. A. Demura; A. Brandis; V. Rosenbach-Belkin; A. Yu. Baryshnikov; A. Scherz

doi:10.1117/12.640051

7 December 2006 Fluorescent and photodynamic properties of near-infrared photosensitizer bacteriochlorophyllide-serine

I. G. Meerovich, I. Yu. Kubasova, N. A. Oborotova, G. A. Meerovich, S. A. Demura, A. Brandis, V. Rosenbach-Belkin, A. Yu. Baryshnikov, A. Scherz

Author Affiliations +

Proceedings Volume 5973, Current Research on Laser Use in Oncology: 2000-2004; 59730G (2006) https://doi.org/10.1117/12.640051
Event: Current Research on Laser Use in Oncology: 2000-2004, 2004, Moscow, Russian Federation

Abstract

Study is devoted to investigation of fluorescent and photodynamic properties of near-infrared photosensitizer bacteriochloriphyllide-serine. The peculiarities of its fluorescence excited by different lasers, dynamics and selectivity of accumulation were investigated. Photodynamic therapy of mice and investigation of tissue de-oxygenation during tumor irradiation were performed. It was shown that bacteriochloriphyllide-serine is an effective photosensitizer for PDT and fluorescent diagnostics of tumors.

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I. G. Meerovich, I. Yu. Kubasova, N. A. Oborotova, G. A. Meerovich, S. A. Demura, A. Brandis, V. Rosenbach-Belkin, A. Yu. Baryshnikov, and A. Scherz "Fluorescent and photodynamic properties of near-infrared photosensitizer bacteriochlorophyllide-serine", Proc. SPIE 5973, Current Research on Laser Use in Oncology: 2000-2004, 59730G (7 December 2006); https://doi.org/10.1117/12.640051

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