Automated detection of pulmonary nodules from low-dose computed tomography scans using a two-stage classification system based on local image features

K. Murphy; A. Schilham; H. Gietema; M. Prokop; B. van Ginneken

doi:10.1117/12.713370

29 March 2007 Automated detection of pulmonary nodules from low-dose computed tomography scans using a two-stage classification system based on local image features

K. Murphy, A. Schilham, H. Gietema, M. Prokop, B. van Ginneken

Author Affiliations +

Proceedings Volume 6514, Medical Imaging 2007: Computer-Aided Diagnosis; 651410 (2007) https://doi.org/10.1117/12.713370
Event: Medical Imaging, 2007, San Diego, CA, United States

Abstract

The automated detection of lung nodules in CT scans is an important problem in computer-aided diagnosis. In this paper an approach to nodule candidate detection is presented which utilises the local image features of shape index and curvedness. False-positive candidates are removed by means of a two-step approach using kNN classification. The kNN classifiers are trained using features of the image intensity gradients and grey-values in addition to further measures of shape index and curvedness profiles in the candidate regions. The training set consisted of data from 698 scans while the independent test set comprised a further 142 images. At 84% sensitivity an average of 8.2 false-positive detections per scan were observed.

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K. Murphy, A. Schilham, H. Gietema, M. Prokop, and B. van Ginneken "Automated detection of pulmonary nodules from low-dose computed tomography scans using a two-stage classification system based on local image features", Proc. SPIE 6514, Medical Imaging 2007: Computer-Aided Diagnosis, 651410 (29 March 2007); https://doi.org/10.1117/12.713370

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