Optical coherence computed tomography

Li Li; Lihong V. Wang

doi:10.1117/12.761431

6 February 2008 Optical coherence computed tomography

Li Li, Lihong V. Wang

Proceedings Volume 6855, Complex Dynamics and Fluctuations in Biomedical Photonics V; 68550H (2008) https://doi.org/10.1117/12.761431
Event: SPIE BiOS, 2008, San Jose, California, United States

Abstract

We proposed a novel time-resolved optical tomography, optical coherence computed tomography. It married the key concepts of time-resolved diffuse optical tomography and optical coherence tomography. Both ballistic and multiple-scattered photons were measured at multiple source-detection positions by low-coherence interferometry. It measures the reemitted light with a temporal resolution of 56 femtoseconds, which is much better than the resolution of conventional time-resolved detection systems. A light-tissue interaction model was established using the time-resolved Monte Carlo method. The optical properties were then reconstructed by solving the inverse time-resolved radiative transport problem under the first Born approximation. Our initial results showed the potential of this technology to bridge the gap between diffuse optical tomography and optical coherence tomography.

Citation Download Citation

Li Li and Lihong V. Wang "Optical coherence computed tomography", Proc. SPIE 6855, Complex Dynamics and Fluctuations in Biomedical Photonics V, 68550H (6 February 2008); https://doi.org/10.1117/12.761431

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