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Myocardial Ischemia is a condition which affects millions of people in the U.S. It is known
that a rise in levels of extracellular potassium indicates the onset of this condition. This presentation
demonstrates the fabrication of a unique potassium sensing device which combines a conducting
polymer, polypyrrole, with micro/nano fabrication and nanowire technology. We discuss the
fabrication of gold/polypyrrole electrodes on a flexible polyimide substrate. Conducting polymers
offer numerous advantages when it comes to ion sensing including increased stability in response
while micro/nanofabrication aids in the overall miniaturization. The small size and flexibility makes
this device suitable for future biomedical applications involving implantation. In this presentation,
various electrode structures including nanowire electrodes ware investigated. Testing is conducted
with an electrochemical analyzer where changes in open circuit potentials reflect changes in
potassium ion concentration.
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Vasuda Ramachandran, Hargsoon Yoon, Vijay K. Varadan, "Development of potassium ion sensors using polypyrrole electrodes on a polyimide substrate," Proc. SPIE 6931, Nanosensors and Microsensors for Bio-Systems 2008, 69310H (26 March 2008); https://doi.org/10.1117/12.776834