Pressure-enhanced near-infrared breast imaging: toward cancer patient imaging

Shudong Jiang; Brian W. Pogue; Ashley M. Laughney; Keith D. Paulsen

doi:10.1117/12.808071

12 February 2009 Pressure-enhanced near-infrared breast imaging: toward cancer patient imaging

Shudong Jiang, Brian W. Pogue, Ashley M. Laughney, Keith D. Paulsen

Proceedings Volume 7174, Optical Tomography and Spectroscopy of Tissue VIII; 71740S (2009) https://doi.org/10.1117/12.808071
Event: SPIE BiOS, 2009, San Jose, California, United States

Abstract

An NIRS tomography system that can simultaneously acquire data at three wavelengths has been developed to measure changes in physiological properties with 15 second time resolution. The results of homogenous and heterogeneous blood phantom studies indicated that the R² values between average estimated total hemoglobin (Hb_T) values and blood concentrations are 0.99 and 0.9, respectively. In preliminary normal subject clinical trials, a cohort of normal subjects were tested by acquiring the series images as well as the pressure is adding to and releasing from the breast. The recovered data shown that by adding measurable pressure, Hb_T is reduced and the maximum HbT reduction is correlated to the Body Mass Index.

Citation Download Citation

Shudong Jiang, Brian W. Pogue, Ashley M. Laughney, and Keith D. Paulsen "Pressure-enhanced near-infrared breast imaging: toward cancer patient imaging", Proc. SPIE 7174, Optical Tomography and Spectroscopy of Tissue VIII, 71740S (12 February 2009); https://doi.org/10.1117/12.808071

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