Paper
17 February 2009 Performance analysis of extinction-based localized surface plasmon resonance biosensors in the presence of surface roughness
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Abstract
We investigated the effect of rough surface on the performance of extinction-based localized surface plasmon resonance (LSPR) biosensors. The sensor measures resonance wavelength shifts in transmittance due to biomolecular interactions amplified by periodic nanostructures. The numerical calculation was conducted using rigorous coupled-wave analysis with Gaussian random profiles. The results suggest that, when a surface has a roughness smaller than 2 nm, the sensitivity of an LSPR biosensor is not significantly affected regardless of correlation length (CL). However, we found that extinction peak amplitude and curve width are affected substantially with a decrease in CL. At CL less than 100 nm, surface roughness may induce interference between localized surface plasmons excited by the surface and nanowires, which can lead to significant degradation of sensor performance.
© (2009) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
Kyung Min Byun, Soon Joon Yoon, and Donghyun Kim "Performance analysis of extinction-based localized surface plasmon resonance biosensors in the presence of surface roughness", Proc. SPIE 7192, Plasmonics in Biology and Medicine VI, 71920Z (17 February 2009); https://doi.org/10.1117/12.808597
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KEYWORDS
Biosensors

Nanowires

Refractive index

Surface roughness

Chlorine

Surface plasmons

Nanostructures

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