WERITAS: weighted ensemble of regional image textures for ASM segmentation

Robert Toth; Scott Doyle; Mark Rosen; Arjun Kalyanpur M.D.; Sona Pungavkar M.D.; B. Nicolas Bloch; Elizabeth Genega; Neil Rofsky; Robert Lenkinski; Anant Madabhushi

doi:10.1117/12.812473

27 March 2009 WERITAS: weighted ensemble of regional image textures for ASM segmentation

Robert Toth, Scott Doyle, Mark Rosen, Arjun Kalyanpur M.D., Sona Pungavkar M.D., B. Nicolas Bloch, Elizabeth Genega, Neil Rofsky, Robert Lenkinski, Anant Madabhushi

Author Affiliations +

Proceedings Volume 7259, Medical Imaging 2009: Image Processing; 725905 (2009) https://doi.org/10.1117/12.812473
Event: SPIE Medical Imaging, 2009, Lake Buena Vista (Orlando Area), Florida, United States

Abstract

In this paper we present WERITAS, which is based in part on the traditional Active Shape Model (ASM) segmentation system. WERITAS generates multiple statistical texture features, and finds the optimal weighted average of those texture features by maximizing the correlation between the Euclidean distance to the ground truth and the Mahalanobis distance to the training data. The weighted average is used a multi-resolution segmentation system to more accurately detect the object border. A rigorous evaluation was performed on over 200 clinical images comprising of prostate images and breast images from 1.5 Tesla and 3 Tesla MRI machines via 6 distinct metrics. WERITAS was tested against a traditional multi-resolution ASM in addition to an ASM system which uses a plethora of random features to determine if the selection of features is improving the results rather than simply the use of multiple features. The results indicate that WERITAS outperforms all other methods to a high degree of statistical significance. For 1.5T prostate MRI images, the overlap from WERITAS is 83%, the overlap from the random features is 81%, and the overlap from the traditional ASM is only 66%. In addition, using 3T prostate MRI images, the overlap from WERITAS is 77%, the overlap from the random features is 54%, and the overlap from the traditional ASM is 59%, suggesting the usefulness of WERITAS. The only metrics in which WERITAS was outperformed did not hold any degree of statistical significance. WERITAS is a robust, efficient, and accurate segmentation system with a wide range of applications.

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Robert Toth, Scott Doyle, Mark Rosen, Arjun Kalyanpur M.D., Sona Pungavkar M.D., B. Nicolas Bloch, Elizabeth Genega, Neil Rofsky, Robert Lenkinski, and Anant Madabhushi "WERITAS: weighted ensemble of regional image textures for ASM segmentation", Proc. SPIE 7259, Medical Imaging 2009: Image Processing, 725905 (27 March 2009); https://doi.org/10.1117/12.812473

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