Thermal motion of an optically trapped nanotool

Stephen H. Simpson; Mervyn J. Miles; Simon Hanna

doi:10.1117/12.825926

20 August 2009 Thermal motion of an optically trapped nanotool

Stephen H. Simpson, Mervyn J. Miles, Simon Hanna

Proceedings Volume 7400, Optical Trapping and Optical Micromanipulation VI; 74001W (2009) https://doi.org/10.1117/12.825926
Event: SPIE NanoScience + Engineering, 2009, San Diego, California, United States

Abstract

By using multiple optical traps suitably sized complex bodies can be bound with respect to their positions and orientations. One recent application of this involves the use of an elongated object, equipped with a probe (a "nanotool"), to measure and apply pico-Newton sized forces to, for example, the surface of a cell. This application has been described as an optical atomic force microscope (AFM). Calculations of the mechanical susceptibility of trapped probes, and their hydrodynamic resistance are presented. These quantities are used to assess the subsequent thermal motion of an optically trapped nanotool in the context of the Orstein-Uhlenbeck process. Implications for the resolution and general behavior of the optical AFM referred to above are discussed.

Citation Download Citation

Stephen H. Simpson, Mervyn J. Miles, and Simon Hanna "Thermal motion of an optically trapped nanotool", Proc. SPIE 7400, Optical Trapping and Optical Micromanipulation VI, 74001W (20 August 2009); https://doi.org/10.1117/12.825926

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