Highly specific detection of IL-8 protein using combination tapered fiber optic biosensor dip-probe

Chun-Wei Wang; Rakesh Kapoor

doi:10.1117/12.843284

24 February 2010 Highly specific detection of IL-8 protein using combination tapered fiber-optic biosensor dip-probe

Chun-Wei Wang, Rakesh Kapoor

Proceedings Volume 7559, Optical Fibers and Sensors for Medical Diagnostics and Treatment Applications X; 75590V (2010) https://doi.org/10.1117/12.843284
Event: SPIE BiOS, 2010, San Francisco, California, United States

Abstract

We are reporting detection of IL-8 in a mixed protein solution, using combination tapered fiber-optic biosensor (CTFOB) dip-probe. Sandwich immunoassay was used as the detection technique. The specificity of the sensor was established by using two types of negative control probes. It is demonstrated that with the help of these CTFOB dipprobe we could successfully detect IL-8 with high specificity in protein mixture. The lowest detected concentration of IL-8 was 150 pM.

Citation Download Citation

Chun-Wei Wang and Rakesh Kapoor "Highly specific detection of IL-8 protein using combination tapered fiber-optic biosensor dip-probe", Proc. SPIE 7559, Optical Fibers and Sensors for Medical Diagnostics and Treatment Applications X, 75590V (24 February 2010); https://doi.org/10.1117/12.843284

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