Improved contrast optoacoustic imaging of deep breast tumors using displacement-compensated averaging: phantom studies

Michael Jaeger; Stefan Preisser; Michael Kitz; Martin Frenz

doi:10.1117/12.848028

25 February 2010 Improved contrast optoacoustic imaging of deep breast tumors using displacement-compensated averaging: phantom studies

Michael Jaeger, Stefan Preisser, Michael Kitz, Martin Frenz

Author Affiliations +

Proceedings Volume 7564, Photons Plus Ultrasound: Imaging and Sensing 2010; 75640R (2010) https://doi.org/10.1117/12.848028
Event: SPIE BiOS, 2010, San Francisco, California, United States

Abstract

For real-time optoacoustic imaging of the human body, a linear array transducer and reflection mode optical irradiation is usually preferred. Such a setup, however, results in significant image background, which prevents imaging structures at the ultimate depth limited only by the signal noise level. Therefore we previously proposed a method for image background reduction, based on displacement-compensated averaging (DCA) of image series obtained when the tissue sample under investigation is gradually deformed. Optoacoustic signals and background signals are differently affected by the deformation and can thus be distinguished. The proposed method has now been applied to imaging artificial tumors embedded inside breast phantoms. Optoacoustic images are acquired alternately with pulse-echo images using a combined optoacoustic/ echo-ultrasound device. Tissue deformation is accessed via speckle tracking in pulse echo images, and optoacoustic images are compensated for the local tissue displacement. In that way optoacoustic sources are highly correlated between subsequent images, while background is decorrelated and can therefore be reduced by averaging. We show that breast image contrast is strongly improved and detectability of embedded tumors significantly increased, using the DCA method.

Citation Download Citation

Michael Jaeger, Stefan Preisser, Michael Kitz, and Martin Frenz "Improved contrast optoacoustic imaging of deep breast tumors using displacement-compensated averaging: phantom studies", Proc. SPIE 7564, Photons Plus Ultrasound: Imaging and Sensing 2010, 75640R (25 February 2010); https://doi.org/10.1117/12.848028

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available