An optimized engineering design of imaging probe for time-resolved diffuse optical tomography system

Ling Chen; Ali Hasnain; Nanguang Chen

doi:10.1117/12.904245

29 November 2011 An optimized engineering design of imaging probe for time-resolved diffuse optical tomography system

Ling Chen, Ali Hasnain, Nanguang Chen

Proceedings Volume 8311, Optical Sensors and Biophotonics III; 83110L (2011) https://doi.org/10.1117/12.904245
Event: SPIE/OSA/IEEE Asia Communications and Photonics, 2011, Shanghai, China

Abstract

We proposed an optimized engineering design of an imaging probe for time-resolved diffuse optical tomography system to increase the sensitivity of signal detection from tested objects. With limited number of sources and detectors, we considered an automatic rotational probe to generate more measurement pairs as well as more detection angles, compared to probes with equal number of sources and detectors. We also considered optimizing the arrangements of sources and detectors on the imaging probe to collect more information from the tested domain than those random arrangements. The method for selecting optimized sources' and detectors' positions is based on Cramer-Rao lower bound. Image reconstruction results of semi-infinite domain using phantom experimental data from different patterns of source and detector arrangements are presented. We demonstrated that the optimized source and detector arrangements chosen based on the reconstruction results match the choices from the optimized selecting methods. Thus we selected the optimized sets for the imaging probe.

Citation Download Citation

Ling Chen, Ali Hasnain, and Nanguang Chen "An optimized engineering design of imaging probe for time-resolved diffuse optical tomography system", Proc. SPIE 8311, Optical Sensors and Biophotonics III, 83110L (29 November 2011); https://doi.org/10.1117/12.904245

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available