Optical microscopy with super-resolution by liquid-immersed high-index microspheres

Arash Darafsheh; Nicholaos I. Limberopoulos; John S. Derov; Dennis E. Walker Jr.; Magdalena Durska; Dimitry N. Krizhanovskii; David M. Whittaker; Vasily N. Astratov

doi:10.1117/12.2005896

19 February 2013 Optical microscopy with super-resolution by liquid-immersed high-index microspheres

Arash Darafsheh, Nicholaos I. Limberopoulos, John S. Derov, Dennis E. Walker Jr., Magdalena Durska, Dimitry N. Krizhanovskii, David M. Whittaker, Vasily N. Astratov

Author Affiliations +

Proceedings Volume 8594, Nanoscale Imaging, Sensing, and Actuation for Biomedical Applications X; 85940C (2013) https://doi.org/10.1117/12.2005896
Event: SPIE BiOS, 2013, San Francisco, California, United States

Abstract

We study super-resolution capability of liquid-immersed high refractive index (n~1.9–2.1) barium titanate glass microspheres with diameters from several microns up to hundreds of microns. Imaging is provided in a conventional upright microscope with the spheres placed in a contact position with various semiconductor and metallic nanostructures. Using a commercial Blu-ray disk, we demonstrate an ability to discern 100 nm feature sizes which cannot be resolved by conventional microscopy. Using silver nanowires with diameter about 100 nm, we demonstrate ~1.7 times improvement in spatial resolution compared to conventional diffraction-limited far field microscopy. Using two-dimensional nanoplasmonic arrays, we demonstrate high resolution imaging by using objectives with surprisingly small numerical apertures. The last property is attractive for high-resolution imaging at long working distances. This imaging technique can be used in biomedical microscopy, microfluidics, and nanophotonics applications.

Citation Download Citation

Arash Darafsheh, Nicholaos I. Limberopoulos, John S. Derov, Dennis E. Walker Jr., Magdalena Durska, Dimitry N. Krizhanovskii, David M. Whittaker, and Vasily N. Astratov "Optical microscopy with super-resolution by liquid-immersed high-index microspheres", Proc. SPIE 8594, Nanoscale Imaging, Sensing, and Actuation for Biomedical Applications X, 85940C (19 February 2013); https://doi.org/10.1117/12.2005896

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available