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The papers included in this volume were part of the technical conference cited on the cover and title page. Papers were selected and subject to review by the editors and conference program committee. Some conference presentations may not be available for publication. The papers published in these proceedings reflect the work and thoughts of the authors and are published herein as submitted. The publisher is not responsible for the validity of the information or for any outcomes resulting from reliance thereon. Please use the following format to cite material from this book: Author(s), “Title of Paper,” in Photonic Therapeutics and Diagnostics X, edited by Bernard Choi, et al., Proceedings of SPIE Vol. 8926 (SPIE, Bellingham, WA, 2014) Article CID Number. ISSN: 1605-7422 ISBN: 9780819498397 Published by SPIE P.O. Box 10, Bellingham, Washington 98227-0010 USA Telephone +1 360 676 3290 (Pacific Time) · Fax +1 360 647 1445 Copyright © 2014, Society of Photo-Optical Instrumentation Engineers. Copying of material in this book for internal or personal use, or for the internal or personal use of specific clients, beyond the fair use provisions granted by the U.S. Copyright Law is authorized by SPIE subject to payment of copying fees. The Transactional Reporting Service base fee for this volume is $18.00 per article (or portion thereof), which should be paid directly to the Copyright Clearance Center (CCC), 222 Rosewood Drive, Danvers, MA 01923. Payment may also be made electronically through CCC Online at copyright.com. Other copying for republication, resale, advertising or promotion, or any form of systematic or multiple reproduction of any material in this book is prohibited except with permission in writing from the publisher. The CCC fee code is 1605-7422/14/$18.00. Printed in the United States of America. Publication of record for individual papers is online in the SPIE Digital Library. Paper Numbering: Proceedings of SPIE follow an e-First publication model, with papers published first online and then in print and on CD-ROM. Papers are published as they are submitted and meet publication criteria. A unique, consistent, permanent citation identifier (CID) number is assigned to each article at the time of the first publication. Utilization of CIDs allows articles to be fully citable as soon as they are published online, and connects the same identifier to all online, print, and electronic versions of the publication. SPIE uses a six-digit CID article numbering system in which:
The CID Number appears on each page of the manuscript. The complete citation is used on the first page, and an abbreviated version on subsequent pages. Numbers in the index correspond to the last two digits of the six-digit CID Number. Conference CommitteeSymposium Chairs
Program Track Chair Part A Photonics in Dermatology and Plastic SurgeryConference Chairs
Conference Program Committee
Session Chairs
Part B Therapeutics and Diagnostics in UrologyConference Chairs Conference Program Committee
Session Chairs
Part C Optical Imaging, Therapeutics, and Advanced Technology in Head and Neck Surgery and OtolaryngologyConference Chairs
Conference Program Committee
Session Chairs
Part D Diagnostic and Therapeutic Applications of Light in CardiologyConference Chairs
Conference Program Committee
Session Chairs
Part E Optics in Bone Surgery and DiagnosticsConference Chair Conference Co-chair Conference Program Committee
Session Chairs
IntroductionThe field of Otolaryngology, Head and Neck Surgery continues to be a challenging specialty for the application of novel diagnostic methods and therapeutic concepts. The contributions presented at the conference and issued hereafter reflect the responses to this challenge. The evolution of optical diagnostics, namely optical coherence tomography in its variants, fluorescence imaging, elastic scattering spectroscopy, confocal laser scanning microscopy has proceeded to an extent that most of the research presented is related to in vivo studies compared to more in vitro oriented projects of previous years. Moreover, many practical issues regarding the usability of optical diagnostic devices have been addressed, such as integrating OCT scanners in handheld otoscopes or the automated working distance adjustment for an OCT scanner in a conventional handheld laryngoscope. On the side of basic science, OCT scanners have become capable of scanning vibrational modes of the human tympanic membrane over a wide range of frequencies, thereby confirming data that have been postulated from finite element models in past years. In addition to practical issues concerning the use of photonic imaging devices, increasing their predictive value compared to current diagnostic procedures and standards is of importance. Many workgroups have successfully combined variants of these imaging modalities in order to increase specificity and sensitivity in contrast to one method alone for differentiating benign, pre-malignant and malignant lesions of inner mucosal and outer skin surfaces of the head and neck. Co-registering and co-locating two-dimensional images from different methods and different orientation of the same lesion further helps to understand patterns of cellular growth in the context of pre-malignant and malignant neoplasms. This understanding enables the physician to tailor therapeutic regimes for the benefit of the patient, maximizing therapeutic security while minimizing loss of organ function and adverse effects. In this context, the conference has been co-located with the annual scientific meeting of the Head and Neck Optical Diagnostic Society (HNODS) successfully for the second time. Within the scope of the society is also the propagation of minimally invasive therapeutic concepts in photodynamic therapy. Key research over the past years has been, among others, establishing and validating reliable dosimetry regimes for interstitial and superficial applications of PDT. As photonics diagnostic and therapeutic technology will undoubtedly advance and mature in future years, one of the main challenges will be to propagate its use in clinical settings on a broad scale, generating a broad knowledge base for future research and increasing the quality of medical care in general for a greater public. Brian J. F. Wong Justus F. Ilgner |