Cardiac tissue characterization using near-infrared spectroscopy

Rajinder Singh Moon; Christine P. Hendon

doi:10.1117/12.2036320

4 March 2014 Cardiac tissue characterization using near-infrared spectroscopy

Rajinder Singh Moon, Christine P. Hendon

Proceedings Volume 8926, Photonic Therapeutics and Diagnostics X; 89263N (2014) https://doi.org/10.1117/12.2036320
Event: SPIE BiOS, 2014, San Francisco, California, United States

Abstract

Cardiac tissue from swine and canine hearts were assessed using diffuse reflectance near-infrared spectroscopy (NIRS) ex vivo. Slope measured between 800-880 nm reflectance was found to reveal differences between epicardial fat and normal myocardium tissue. This parameter was observed to increase monotonically from measurements obtained from the onset of radiofrequency ablation (RFA). A sheathe-style fiber optic catheter was then developed to allow real-time sampling of the zone of resistive heating during RFA treatment. A model was developed and used to extract changes in tissue absorption and reduced scattering based on the steady-state diffusion approximation. It was found that key changes in tissue optical properties occur during application of RF energy and can be monitored using NIRS. These results encourage the development of NIRS integrated catheters for real-time guidance of the cardiac ablation treatment.

Citation Download Citation

Rajinder Singh Moon and Christine P. Hendon "Cardiac tissue characterization using near-infrared spectroscopy", Proc. SPIE 8926, Photonic Therapeutics and Diagnostics X, 89263N (4 March 2014); https://doi.org/10.1117/12.2036320

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