Modeling and experimental validation of angular radiance and distance-dependent radiance in a turbid medium

Lingling Liu; Chenxi Li; Huijuan Zhao; Xi Yi; Feng Gao; Wei Meng; Yiming Lu

doi:10.1117/12.2036548

4 March 2014 Modeling and experimental validation of angular radiance and distance-dependent radiance in a turbid medium

Lingling Liu, Chenxi Li, Huijuan Zhao, Xi Yi, Feng Gao, Wei Meng, Yiming Lu

Author Affiliations +

Proceedings Volume 8952, Biomedical Applications of Light Scattering VIII; 895218 (2014) https://doi.org/10.1117/12.2036548
Event: SPIE BiOS, 2014, San Francisco, California, United States

Abstract

Radiance is sensitive to the variations of tissue optical parameters, such as absorption coefficient μ_a, scattering coefficient μ_s, and anisotropy factor g. Therefore, similar to fluence, radiance can be used for tissue characterization. Compared with fluence, radiance has the advantage of offering the direction information of light intensity. Taking such advantage, the optical parameters can be determined by rotating the detector through 360 deg with only a single optode pair. Instead of the translation mode used in the fluence-based technologies, the Rotation mode has less invasiveness in the clinical diagnosis. This paper explores a new method to obtain the optical properties by measuring the distribution of light intensity in liquid phantom with only a single optode pair and the detector rotation through 360 deg. The angular radiance and distance-dependent radiance are verified by comparing experimental measurement data with Monte Carlo (MC) simulation for the short source-detector separations and diffusion approximation for the large source-detector separations. Detecting angular radiance with only a single optode pair under a certain source-detection separation will present a way for prostate diagnose and light dose calculation during the photon dynamic therapy (PDT).

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Lingling Liu, Chenxi Li, Huijuan Zhao, Xi Yi, Feng Gao, Wei Meng, and Yiming Lu "Modeling and experimental validation of angular radiance and distance-dependent radiance in a turbid medium", Proc. SPIE 8952, Biomedical Applications of Light Scattering VIII, 895218 (4 March 2014); https://doi.org/10.1117/12.2036548

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KEYWORDS

Sensors

Tissue optics

Monte Carlo methods

Distance measurement

Optical properties

Photon transport

Liquids

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