Photo-nano-therapy for bactericidal using graphene oxide

Jie Wu; Jinchao Gao M.D.; Yujia Xie; Xianpei Chen

doi:10.1117/12.2079438

9 March 2015 Photo-nano-therapy for bactericidal using graphene oxide

Jie Wu, Jinchao Gao M.D., Yujia Xie, Xianpei Chen

Proceedings Volume 9324, Biophotonics and Immune Responses X; 93240Z (2015) https://doi.org/10.1117/12.2079438
Event: SPIE BiOS, 2015, San Francisco, California, United States

Abstract

Graphene oxide (GO) have attracted more attention because of the universal property, and rapidly applied in biomedical field, such as drug carriers, imaging or therapy. GO has been considered biocompatible with a broad variety of eukaryotic cells. Here, we show that, GO could kill Gram-positive and –negative bacteria rapidly and efficiently, with light irradiation. We investigated the efficacy of GO on bactericidal activation, the antibacterial activity of GO is concentration dependent, and enhanced by light irradiation. Our results describe the discovery of a property of partially GO as a potent antibacterial agent. The results showed that GO has excellent antibacterial activity when the concentration is above 300 μg/mL, the antibacterial rate can reached 100% when incubated with E. coli and B. subtilis for 4h.

Citation Download Citation

Jie Wu, Jinchao Gao M.D., Yujia Xie, and Xianpei Chen "Photo-nano-therapy for bactericidal using graphene oxide", Proc. SPIE 9324, Biophotonics and Immune Responses X, 93240Z (9 March 2015); https://doi.org/10.1117/12.2079438

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