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The papers included in this volume were part of the technical conference cited on the cover and title page. Papers were selected and subject to review by the editors and conference program committee. Some conference presentations may not be available for publication. The papers published in these proceedings reflect the work and thoughts of the authors and are published herein as submitted. The publisher is not responsible for the validity of the information or for any outcomes resulting from reliance thereon. Please use the following format to cite material from this book: Author(s), “Title of Paper,” in Medical Imaging 2015: Biomedical Applications in Molecular, Structural, and Functional Imaging, edited by Barjor Gimi, Robert C. Molthen, Proceedings of SPIE Vol. 9417 (SPIE, Bellingham, WA, 2015) Article CID Number. ISSN: 1605-7422 ISBN: 9781628415070 Published by SPIE P.O. Box 10, Bellingham, Washington 98227-0010 USA Telephone +1 360 676 3290 (Pacific Time) · Fax +1 360 647 1445 Copyright © 2015, Society of Photo-Optical Instrumentation Engineers. Copying of material in this book for internal or personal use, or for the internal or personal use of specific clients, beyond the fair use provisions granted by the U.S. Copyright Law is authorized by SPIE subject to payment of copying fees. The Transactional Reporting Service base fee for this volume is $18.00 per article (or portion thereof), which should be paid directly to the Copyright Clearance Center (CCC), 222 Rosewood Drive, Danvers, MA 01923. Payment may also be made electronically through CCC Online at copyright.com. Other copying for republication, resale, advertising or promotion, or any form of systematic or multiple reproduction of any material in this book is prohibited except with permission in writing from the publisher. The CCC fee code is 1605-7422/15/$18.00. Printed in the United States of America. Publication of record for individual papers is online in the SPIE Digital Library. Paper Numbering: Proceedings of SPIE follow an e-First publication model, with papers published first online and then in print. Papers are published as they are submitted and meet publication criteria. A unique citation identifier (CID) number is assigned to each article at the time of the first publication. Utilization of CIDs allows articles to be fully citable as soon as they are published online, and connects the same identifier to all online, print, and electronic versions of the publication. SPIE uses a six-digit CID article numbering system in which:
The CID Number appears on each page of the manuscript. The complete citation is used on the first page, and an abbreviated version on subsequent pages. AuthorsNumbers in the index correspond to the last two digits of the six-digit citation identifier (CID) article numbering system used in Proceedings of SPIE. The first four digits reflect the volume number. Base 36 numbering is employed for the last two digits and indicates the order of articles within the volume. Numbers start with 00, 01, 02, 03, 04, 05, 06, 07, 08, 09, 0A, 0B…0Z, followed by 10-1Z, 20-2Z, etc. Abidin, Anas Z., 0M, 1E, 1F, 1M, 1N Abramson, Richard G., 03, 07 Agarwal, Shubhangi, 14, 1J Ahmad, Rizwan, 06 Ahn, Chi Young, 28 Al-Louzi, Omar, 0P Amouriq, Y., 2Q, 2R Anderson, Adam, 1T Anderson, Erik, 0T Andescavage, Nickie, 0O Andreana, S., 1D Andrews, Peter M., 0T Appenzeller, Simone, 2A Arens, Raanan, 2J Armspach, Jean-Paul, 0K Arranz, Alicia, 23 Autrusseau, F., 2Q, 2R Avison, Malcom J., 0A Axel, Leon, 0G Azad, Md Khurshidul, 2N Azad, Yoo-Jin, 2G Baier, Robert, 0W Bankson, James A., 02, 0B Bao, Chengpeng, 2U Bala Nivetha, K., 1X Baucom, Rebeccah B., 07 Bauer, Jan S., 1E Baum, Thomas, 1E Bednarek, Daniel R., 0V, 0W, 1D, 26 Benavides, Erika, 1B Ben-Eliezer, Noam, 0G Bennink, Edwin, 0I, 1Q Benvenuto, James, 2B Bertoldo, Alessandra, 1U Bezerra, Hiram G., 0Y, 0Z Bhagalia, Roshni, 12 Bhargava, Maneesh, 18 Bhargava, Rohit, 20 Bhattacharya, Pratip, 02 Bhattacharyya, Rajan, 2B Blackford, Ethan B., 2D Blank, Aharon, 06 Blazejewska, Anna I., 0N Block, Tobias, 0G Bluemke, Emma, 17, 2O Bodenstedt, Sebastian, 2G Boffano, Carlo, 1U Botsivali, Maria, 10 Boutchko, Rostyslav, 0X Brogi, Edi, 12 Bruzzone, Maria Grazia, 1U Budin, Francois, 1C, 1R Burke, Ryan P., 07 Busovaca, Edgar, 1S Buss, Claudia, 1R Bustillo, Juan, 1V Calabresi, Peter A., 0P Calhoun, Vince D., 1V Cao, Kunlin, 12 Capaldi, D. P. I., 16, 1A Carass, Aaron, 0P Carson, Daniel, 02 Castellaro, Marco, 1U Castro, Marcelo A., 27 Caucutt, Jason, 0N Cebral, Juan R., 27 Cevidanes, Lucia, 1B, 1C Chalak, Lina, 1P Chandarana, Hersh, 0G Chatziioannou, Sofia, 10 Checefsky, Walter A., 1E, 1F Chen, Georgia Zhuo, 0Q Chen, Shoupu, 2F Chen, Y, 0T Cherel, Marie, 1R Chien, Aichi, 27 Choi, Jung-il, 28 Cloos, Martijn, 0G Coan, Paola, 1F Cone, Roger, 2I Constantinou, Pamela, 02 Costa, André L., 2A Crauste, E., 2R Cunningham, Ian A., 16, 1A, 2O Dankbaar, Jan Willem, 0I de Jong, Hugo W. A. M., 0I, 1Q Delles, Michael, 2G Dhanantwari, Amar, 0Y, 0Z Dhurjaty, Sreeram, 2K Diaz Martinez, Myriam, 2I Diemoz, Paul C., 1F Dighe, Manjiri, 0N Dilger, Samantha K. N., 29 Dillmann, Rüdiger, 2G Ding, Mingyue, 15 Dong, Di, 23, 24 Drangova, Maria, 25 D’Souza, Adora M., 0M, 1M, 1N D’Souza, Alisha V., 13 Du, Yuhui, 1V Duma, Virgil-Florin, 0U Dziak, R., 1D Eck, Brendan L., 0Y, 0Z Elliott, Jonathan T., 13 Entringer, Sonja, 1R Eon, Rehman S., 1K Esmaeili-Firidouni, Pardis, 1S Estepp, Justin R., 2D Evangelou, Iordanis E., 0O Fabbri, Daniel, 2C Fahmi, Rachid, 0Y, 0Z Fares, Anas, 0Y Fei, Baowei, 0Q Feiglin, David, 11 Feng, Li, 0G Fenster, Aaron, 17, 2O Fiehler, Jens, 2H Flint, Katelyn M., 04 Flood, Ann Barry, 1I Forkert, Nils Daniel, 2H Foucher, Jack, 0K Freuchet, E., 2Q Fujita, H., 22 Fuqua, Christopher, 0Z Gaede, Stewart, 09 Ganesan, A. R., 1Z Gao, Yurui, 1T Garvin, Mona K., 21 Garwood, Michael, 18 Gatenby, Christopher, 0N Geethanath, Sairam, 1J Georgakopoulos, Alexandros, 10 Ghamari-Langroudi, Masoud, 2I Gifford, Aliya, 0A, 2I Gilmore, John, 1R Gimi, Barjor, 1I Giumelli, B., 2R Glasser, Matthew F., 1R Goldberg, Ezequiel, 27 Gomes, Liliane, 1C Gore, John C., 0C Gorenstein, David, 02 Grisan, Enrico, 1U Gruen, Marnie L., 0C Grundfest, Warren, 1G Guédon, Jp., 2Q, 2R Gullberg, Grant T., 0X Gunn, Jason R., 13 Guo, F., 17 Guo, Hengchang, 0T Guo, Yingkun, 0D, 0E, 1H Gutierrez, Marco A., 0S Gyacskov, Igor, 2O Haasbeek, Cornelis J. A., 19 Haddad, Seyyed M. H., 25 Hammond, Emily, 29 Hasty, Alyssa H., 0C He, Hao, 1V Henry, Brian, 2N Hobbs, Susan K., 0M, 1E, 1F, 1M, 1N Holton, Sarah E., 20 Horsch, Alexander D., 0I Hu, Jingzhe, 02 Hu, Zhenhua, 2U Huang, Hao, 1P Huber, Markus B., 1F Huynh, Khang T., 1K Igarashi, Takahiro, 0D, 0E, 1H Ingbar, David H., 18 Inge, Landon J., 14 Ionita, Ciprian N., 0V, 0W, 1D, 26 Itoh, H., 2P Jackson, Greg, 1P Jagust, William, 0X Jain, A., 1D Jang, Jaeseong, 28 Janve, Vaibhav, 1T Jeon, Kiwan, 28 Jeon, Tina, 1P Jiang, Tianzi, 1V Jimenez, Carlos, 0W, 26 Johnsen, Allison M., 03 Johnson, K., 0J Jones, Thomas R., 1V Joshi, Shantanu H., 1S Judisch, Alexandra, 29 Kallergi, Maria, 10 Kaneko, C., 22 Kang, Min Kyu, 08 Karami, Elham, 09 Kardon, Randy H., 21 Kauczor, Hans-Ulrich, 2G Kawata, Y., 2P Khobragade, Parag, 0V, 1D Kim, Namkug, 2V King, M. A., 0J Kingston, A., 2Q Kligerman, Seth, 08 Kmiec, Maciej M., 1I Knoll, Florian, 0G Kobayashi, Naoharu, 18 Kodibagkar, Vikram D., 0F, 14, 1J Krol, Andrzej, 11 Kupersmith, Mark J., 21 Kuppusamy, Periannan, 06 Lake, David S., 1K Landman, Bennett A., 07, 1T, 2C Lang, Andrew, 0P Larson, Steven M., 12 Lavalley, Cathy, 11 Lee, Changhoon, 28 Lee, Christopher P., 07 Lee, Kevin, 1R Lee, Minho, 2V Lee, Sang Min, 2V Lee, Ting-Yim, 09 Lei, Jianxun, 18 Leistritz, Lutz, 0M Lemos, Pedro A., 0S Levi, Jacob, 0Y Ley, Sebastian, 2G Li, Chunfang, 15 Licskai, Christopher, 2O Limperopoulos, Catherine, 0O Lindenmaier, Tamas J., 2O Lindsay, C., 0J Lisi, Michele, 11 Liu, Haijuan, 15 Liu, Hong, 2K Liu, Shuwei, 1P Liu, Xia, 2U Liu, Yang, 1O Lotufo, Roberto A., 2A Lu, Guolan, 0Q Lu, Wei, 08 Macedo, Maysa M. G., 0S Manduca, Armando, 1K Manescu, Adrian, 0U Mansy, Hansen A., 2N Marron, Steve, 1B Matsumoto, Monica M. S., 2J Mattonen, Sarah A., 19 McCormack, D. G., 16 McGrath, Mary, 11 Mckown, Susan, 0N McMurray, Brandon, 2N Mellinghoff, Ingo K., 12 Menychtas, Dimitrios, 10 Mielniczuk, Lisa, 2O Miga, Michael I., 03, 04 Millin, Rachel, 2B Millward, Niki Zacharias, 02 Minami, K., 2P Mishra, Virendra, 1P Mitra, Debasis, 0X Mokin, M., 26 Morgan, John, 29 Mukherjee, J. M., 0J Mura, Marco, 2O Murata, C., 22 Nagarajan, Mahesh B., 0M, 1E, 1F, 1M, 1N Nakano, Y., 2P Naveed, Muhammad, 11 Negrutiu, Meda Lavinia, 0U Nemani, Venkata K., 1I Nguyen, Tung, 1C Ni, Kang-Yu, 2B Nica, Luminita, 0U Niki, N., 2P Oh, Sang Young, 2V O’Hara, R., 26 Ohmatsu, H., 2P Olivier, P., 0J Ong, Henry H., 0C Oosterbroek, Jaap, 0I, 1Q Otazo, Ricardo, 0G Ouyang, Austin, 1P Palma, David A., 19 Pan, Hui, 0X Paniagua, Beatriz, 1B, 1C Papour, Asael, 1G Parraga, Grace, 16, 17, 1A, 2O Parvathaneni, Prasanna, 1T Peloc, Nora L., 27 Pera, Juliette, 1C Pike, D., 16 Pilet, P., 2R Plassard, Andrew J., 2C Podoleanu, Adrian Gh., 0U Pogue, Brian W., 13 Politis, Nikolaos, 10 Poulose, Benjamin K., 07 Prasanth, K. V., 20 Prince, Jerry L., 0P Putman, Christopher M., 27 Qin, Xulei, 0Q Qiu, Yuchen, 2K Rajchl, M., 17 Rasmussen, Jerod, 1R Recur, B., 2Q Rengier, Fabian, 2G Ripoll, Jorge, 23 Rittner, Letícia, 2A Rollins, Nancy, 1P Roquet, Daniel, 0K Royston, Thomas, 2N Rudin, Stephen, 0V, 0W, 1D, 26 Ruellas, Antonio Carlos, 1B Russ, M., 26 Rychert, Kevin M., 1I Saidha, Shiv, 0P Sakai, H., 2P Samani, Abbas, 09, 25 Samkoe, Kimberley S., 13 Sandler, Richard H., 2N Schilling, Kurt G., 1T Senan, Suresh, 19 Seo, Jin Keun, 28 Seo, Joon Beom, 2V Serag, Ahmed, 0O Seshamani, Sharmishtaa, 0N Setlur Nagesh, S. V., 0W, 1D, 26 Shao, L., 0J Sheikh, Khadija, 2O Shen, Chunxu, 15 Shen, Jiahui, 1L Shi, Liangliang, 23, 24 Sibony, Patrick A., 21 Siddiqui, Adnan, 0W, 26 Sieren, Jessica C., 29 Sin, Sanghun, 2J Sinescu, Cosmin, 0U Sivarajan, Muraleedharan, 1P Sklan, Judah E. S., 2C Snyder, Kenneth, 0V, 0W Sodickson, Daniel K., 0G Song, SuTao, 1O Song, Tianming, 2U Song, X., 0J Sood, Anil, 02 Sood, Anup, 12 Sourty, Marion, 0K Stafsudd, Oscar, 1G Stoyles, Nicholas, 29 Studholme, Colin, 0N Styner, Martin, 1C, 1R Sui, Jing, 1V Sujatha, N., 1X, 1Z Sun, Peizhen, 1T Sun, Phillip Zhe, 0D, 0E, 1H Sunkara, S. K., 1D Sunkara, S., 1D Svenningsen, S., 17, 1A Swartz, Harold M., 1I Swingle, Emily K., 0P Takimura, Celso K., 0S Tan, Maxine, 2K Tarroni, Giacomo, 1U Taylor, Zach, 1G Teramoto, A., 22 Thompson, Paul M., 1S Thoraval, Laurent, 0K Tian, Jie, 23, 24, 2U Tichauer, Kenneth M., 13 Tiwari, Saumya, 20 Tokumoto, Y., 2P Tong, Yubing, 2J Torigian, Drew A., 2J Towse, Theodore F., 0A Tsai, Halley, 1E Twig, Ygal, 06 Udayakumar, K., 1Z Udupa, Jayaram K., 2J Umetani, K., 2P Unterhinninghofen, Roland, 2G Utecht, Lynn, 18 Valcour, Victor, 1S Van Essen, David C., 1R Velthuis, Birgitta K., 0I, 1Q Vembar, Mani, 0Y, 0Z Vidya Shankar, Rohini, 0F, 14, 1J Viergever, Max A., 0I, 1Q von Tengg-Kobligk, Hendrik, 2G Wack, David, 0V Wade, Benjamin S. C., 1S Wadhwa, Pathik D., 1R Walker, Christopher M., 0B Walker, Ronald C., 0A Wang, Dongsheng, 0Q Wang, Hsing-Wen, 0T Wang, Jiahui, 08 Wang, Jui-Kai, 21 Wang, Jun, 23, 24 Wang, Kun, 2U Wang, Xixi, 0M, 1E, 1M, 1N Wang, Yalin, 1S Ward, Aaron D., 19 Webb, Corey D., 0C Weis, Jared A., 03, 04 Weiss, P., 2R Welch, E. Brian, 0A, 0C, 2I White, James A., 25 Whiting, Nicholas, 02 Wile, Geoffrey E., 03 Williams, Benjamin B., 1I Wilson, David L., 0Y, 0Z Wismüller, Axel, 0M, 1E, 1F, 1M, 1N Wolford, Larry, 1B Wolfson, Helen, 06 Wood, Rachel P., 0V, 0W Wu, Hao, 0Y Wu, Kaizhi, 15 Wu, Renhua, 1H Xiao, Gang, 1H Xu, Zhoubing, 07 Yang, Xin, 24 Yang, Xueqian, 0L Yang, Yujie, 23, 24 Yankeelov, Thomas E., 03, 04 Yao, Li, 0L, 1L Ying, Leslie, 0V Yoganand, Aradhana, 0W You, Wonsang, 0O Yu, Qiaowen, 1P Yu, Qingbao, 1V Yuan, J., 17 Zaldarriaga Consing, Kirsten, 1R Zha, N., 16 Zhang, Gaoyan, 1L Zhang, JiaCai, 1O Zhang, Qiushi, 0L Zhao, Xiaojie, 0L, 1L Zheng, Bin, 2K Zhou, Iris Yuewen, 0D, 0E, 1H Zhou, Qibing, 15 Zhu, Chaozhe, 0L, 1L Zhu, Gang, 1I Zong, Xinying, 20 Conference CommitteeSymposium Chairs
Conference Chairs
Conference Program Committee
Session Chairs IntroductionThe Biomedical Applications in Molecular, Structural, and Functional Imaging conference held at Renaissance Orlando at SeaWorld in Orlando, Florida was a tremendous success. There was a tremendous boost in the number of abstracts submitted and conference attendees over previous years. Chairs Barjor Gimi and Robert Molthen welcomed Daniel Sodickson from New York University, who delivered a visionary and inspiring talk on the renaissance in rapid imaging. The talk highlighted developments in hardware, image acquisition, and reconstruction that spanned multiple modalities and convincingly presented why the medical imaging field was poised for a quantum leap in the area of rapid imaging. The diverse sessions included Novel Imaging Techniques and Applications; Innovations in Image Processing; Novel MR Techniques and Applications; Neurological Imaging; fMRI; Optical; Fluids and Cardiovascular; Cancer Imaging; Lung; and Bone, along with pleasant lunches and productive coffee breaks. The poster session was lively with numerous posters presenting very high-quality work. The judges selected Treatment planning for image-guided neuro-vascular interventions using patient-specific 3D printed phantoms by Megan K. Russ from The University at Buffalo for the poster prize, with honorable mentions for Simplified correction of B1 inhomogeneity for chemical exchange saturation transfer (CEST) MRI measurement with surface transceiver coil by Phillip Zhe Sun of Massachusetts General Hospital, Investigating the use of mutual information and non-metric clustering for functional connectivity analysis on resting-state functional MRI by XiXi Wang of University of Rochester Medical Center, and Automated pipeline to analyze non-contact infrared images of the paraventricular nucleus specific leptin receptor knock-out mouse model by Myriam Diaz Martinez of Vanderbilt University Medical Center. Barjor Gimi Robert C. Molthen 2015 Medical Imaging Award RecipientsRobert F. Wagner Best Student Paper Award Robert F. Wagner was an active scientist in the SPIE Medical Imaging meeting, starting with the first meeting in 1972 and continuing throughout his career. He ensured that the BRH, and subsequently the CDRH, was a sponsor for the early and subsequent Medical Imaging meetings, helping to launch and ensure the historical success of the meeting. The Robert F. Wagner All-Conference Best Student Paper Award (established 2014) is acknowledgment of his many important contributions to the Medical Imaging meeting and his many important advances to the field of medical imaging. This award is cosponsored by: 2015 Recipients: First Place: Automatic discrimination of color retinal images using the bag of words approach (9414-54) I. Sadek, D. Sidibé, F. Meriaudeau, Univ. of Burgundy (France) Second Place: Automated pulmonary lobar ventilation measurements using volume-matched thoracic CT and MRI (9417-42) F. Guo, S. Svenningsen, E. Bluemke, M. Rajchl, J. Yuan, A. Fenster, G. Parraga, The Univ. of Western Ontario (Canada) Conference Awards 2015 Recipients: Cum Laude Poster Award: Treatment planning for image-guided neuro-vascular interventions using patient-specific 3D printed phantoms [9417-79] Megan K. Russ, Ryan P. O’Hara, Swetadri Vasan Setlur Nagesh, Maxim Mokin, Carlos Jimenez, Adnan H. Siddiqui, Daniel R. Bednarek, Stephen Rudin, Ciprian N. Ionita, Univ. at Buffalo (United States) |