Optical neural stimulation modeling on degenerative neocortical neural networks

M. Zverev; F. Fanjul-Vélez; I. Salas-García; J. L. Arce-Diego

doi:10.1117/12.2183472

14 July 2015 Optical neural stimulation modeling on degenerative neocortical neural networks

M. Zverev, F. Fanjul-Vélez, I. Salas-García, J. L. Arce-Diego

Proceedings Volume 9536, Advanced Microscopy Techniques IV; and Neurophotonics II; 95361I (2015) https://doi.org/10.1117/12.2183472
Event: European Conferences on Biomedical Optics, 2015, Munich, Germany

Abstract

Neurodegenerative diseases usually appear at advanced age. Medical advances make people live longer and as a consequence, the number of neurodegenerative diseases continuously grows. There is still no cure for these diseases, but several brain stimulation techniques have been proposed to improve patients’ condition. One of them is Optical Neural Stimulation (ONS), which is based on the application of optical radiation over specific brain regions. The outer cerebral zones can be noninvasively stimulated, without the common drawbacks associated to surgical procedures. This work focuses on the analysis of ONS effects in stimulated neurons to determine their influence in neuronal activity. For this purpose a neural network model has been employed. The results show the neural network behavior when the stimulation is provided by means of different optical radiation sources and constitute a first approach to adjust the optical light source parameters to stimulate specific neocortical areas.

Citation Download Citation

M. Zverev, F. Fanjul-Vélez, I. Salas-García, and J. L. Arce-Diego "Optical neural stimulation modeling on degenerative neocortical neural networks", Proc. SPIE 9536, Advanced Microscopy Techniques IV; and Neurophotonics II, 95361I (14 July 2015); https://doi.org/10.1117/12.2183472

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available