Morphology and biomechanics of human heart

Natalia O. Chelnokova; Anastasiya A. Golyadkina; Irina V. Kirillova; Asel V. Polienko; Dmitry V. Ivanov

doi:10.1117/12.2208423

9 March 2016 Morphology and biomechanics of human heart

Natalia O. Chelnokova, Anastasiya A. Golyadkina, Irina V. Kirillova, Asel V. Polienko, Dmitry V. Ivanov

Proceedings Volume 9710, Optical Elastography and Tissue Biomechanics III; 971013 (2016) https://doi.org/10.1117/12.2208423
Event: SPIE BiOS, 2016, San Francisco, California, United States

Abstract

Object of study: A study of the biomechanical characteristics of the human heart ventricles was performed. 80 hearts were extracted during autopsy of 80 corpses of adults (40 women and 40 men) aged 31-70 years. The samples were investigated in compliance with the recommendations of the ethics committee.

Methods: Tension and compression tests were performed with help of the uniaxial testing machine Instron 5944. Cardiometry was also performed.

Results: In this work, techniques for human heart ventricle wall biomechanical properties estimation were developed. Regularities of age and gender variability in deformative and strength properties of the right and left ventricle walls were found. These properties were characterized by a smooth growth of myocardial tissue stiffness and resistivity at a relatively low strain against reduction in their strength and elasticity from 31-40 to 61-70 years. It was found that tissue of the left ventricle at 61-70 years had a lower stretchability and strength compared with tissues of the right ventricle and septum. These data expands understanding of the morphological organization of the heart ventricles, which is very important for the development of personalized medicine. Taking into account individual, age and gender differences of the heart ventricle tissue biomechanical characteristics allows to rationally choosing the type of patching materials during reconstructive operations on heart.

Citation Download Citation

Natalia O. Chelnokova, Anastasiya A. Golyadkina, Irina V. Kirillova, Asel V. Polienko, and Dmitry V. Ivanov "Morphology and biomechanics of human heart", Proc. SPIE 9710, Optical Elastography and Tissue Biomechanics III, 971013 (9 March 2016); https://doi.org/10.1117/12.2208423

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