Cerebral hemodynamics and oxygen metabolism versus the bispectral index during propofol-induced anesthesia

Susanna Tagliabue; Claus Lindner; Ivette Chochrrón da Prat; Ángela Sánchez-Guerrero; Isabel Serra Mochales; Michal Kacprzak; Federica Maruccia; Udo M. Weigel; Miriam de Nadal; Juan Sahuquillo; Turgut Durduran

doi:10.1117/12.2608237

7 March 2022 Cerebral hemodynamics and oxygen metabolism versus the bispectral index during propofol-induced anesthesia

Susanna Tagliabue, Claus Lindner, Ivette Chochrrón da Prat, Ángela Sánchez-Guerrero, Isabel Serra Mochales, Michal Kacprzak, Federica Maruccia, Udo M. Weigel, Miriam de Nadal, Juan Sahuquillo, Turgut Durduran

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Proceedings Volume PC11945, Clinical and Translational Neurophotonics 2022; PC1194503 (2022) https://doi.org/10.1117/12.2608237
Event: SPIE BiOS, 2022, San Francisco, California, United States

Abstract

One sedative drug to induce anesthesia during surgery is propofol. It diminishes the cerebral metabolic rate of oxygen (CMRO2), preventing memory formation and is coupled with a decrease in the cerebral blood flow (CBF). Anesthesia depth is commonly monitored by the bispectral index (BIS) to avoid awareness. Optical hybrid near-infrared spectroscopies have the potential to assess CMRO2 and other physiological signals (i.e. CBF). Optical signals acquired alongside BIS in surgeries were compared to it and provided additional information. Overall, agreement was found at different levels (group analysis, single subject analysis and simultaneity in time of changes).

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Susanna Tagliabue, Claus Lindner, Ivette Chochrrón da Prat, Ángela Sánchez-Guerrero, Isabel Serra Mochales, Michal Kacprzak, Federica Maruccia, Udo M. Weigel, Miriam de Nadal, Juan Sahuquillo, and Turgut Durduran "Cerebral hemodynamics and oxygen metabolism versus the bispectral index during propofol-induced anesthesia", Proc. SPIE PC11945, Clinical and Translational Neurophotonics 2022, PC1194503 (7 March 2022); https://doi.org/10.1117/12.2608237

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KEYWORDS

Bismuth

Oxygen

Hemodynamics

Mode conditioning cables

Surgery

Cerebral blood flow

Consciousness

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