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17 March 2023 3D printed freeform micro-optics for OCT coronary tissue imaging
Radhika K. Poduval, Fang Hou, Alejandro E. Ortega, Shoumik Lodh, Aditya Kumar, Ashwin Panikkar, Hinnerk Schulz-Hildebrandt, Lillian Wang, Joseph A. Gardecki, Farouc A. Jaffer M.D., Guillermo J. Tearney M.D.
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Proceedings Volume PC12356, Endoscopic Microscopy XVIII; PC123560D (2023) https://doi.org/10.1117/12.2651300
Event: SPIE BiOS, 2023, San Francisco, California, United States
Abstract
Micro-optical coherence tomography (µOCT), is an emerging optical imaging approach enabling visualization of tissue microstructures at near cellular level. Small form-factor fiber-optic probes are needed to enable uOCT devices for minimally invasive diagnostic procedures such as coronary catheterization for atherosclerosis evaluation. Manufacturing complexities associated with miniaturizing current fiber-optic probes limit their optical and mechanical performance. We will present details of the design and construction of these miniaturized µOCT probes comprising TPL-based 3D printed optics, along with pre-clinical imaging results from an animal model. This probe is capable of lateral resolution of 5 µm and EDOF exceeding 850 µm in tissue.
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© (2023) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
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Radhika K. Poduval, Fang Hou, Alejandro E. Ortega, Shoumik Lodh, Aditya Kumar, Ashwin Panikkar, Hinnerk Schulz-Hildebrandt, Lillian Wang, Joseph A. Gardecki, Farouc A. Jaffer M.D., and Guillermo J. Tearney M.D. "3D printed freeform micro-optics for OCT coronary tissue imaging", Proc. SPIE PC12356, Endoscopic Microscopy XVIII, PC123560D (17 March 2023); https://doi.org/10.1117/12.2651300
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KEYWORDS
Tissues
Micro optics
3D image processing
Optical coherence tomography
Fiber optics
Stereoscopy
Tomography
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