Multipath contrast of optical coherence tomography for early cancer detection

Jeanie Malone; Adrian Tanskanen; Lien Hoang M.D.; Jessica McAlpine M.D.; Calum MacAulay; Pierre Lane

doi:10.1117/12.2650504

6 March 2023 Multipath contrast of optical coherence tomography for early cancer detection

Jeanie Malone, Adrian Tanskanen, Lien Hoang M.D., Jessica McAlpine M.D., Calum MacAulay, Pierre Lane

Author Affiliations +

Proceedings Volume PC12371, Multimodal Biomedical Imaging XVIII; PC1237107 (2023) https://doi.org/10.1117/12.2650504
Event: SPIE BiOS, 2023, San Francisco, California, United States

Abstract

We hypothesize that there may be cancer-sensitive image biomarkers present in a novel image processing technique. We leverage the multipath artifacts derived from higher order modes that present in double clad fiber-based OCT systems, which are sensitive to scattering angle and as such may be sensitive to sub-resolution features such as nuclear density and size. This work explores multipath contrast in previously collected clinical imaging data; preliminary work has found that this technique can distinguish cancerous and non-cancerous fallopian tube specimens.

Conference Presentation

Citation Download Citation

Jeanie Malone, Adrian Tanskanen, Lien Hoang M.D., Jessica McAlpine M.D., Calum MacAulay, and Pierre Lane "Multipath contrast of optical coherence tomography for early cancer detection", Proc. SPIE PC12371, Multimodal Biomedical Imaging XVIII, PC1237107 (6 March 2023); https://doi.org/10.1117/12.2650504

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

;

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE