Photon mayhem: polarized light for structural and functional assessment of biological tissues

I. Alex Vitkin

doi:10.1117/12.2683831

5 October 2023 Photon mayhem: polarized light for structural and functional assessment of biological tissues

I. Alex Vitkin

Proceedings Volume PC12690, Polarization Science and Remote Sensing XI; PC1269003 (2023) https://doi.org/10.1117/12.2683831
Event: SPIE Optical Engineering + Applications, 2023, San Diego, California, United States

Abstract

Multiple scattering of light in biological tissues rapidly scrambles polarization, so polarimetric biomedicine is challenging. Nevertheless, there are ways to mitigate these and other tissue-specific challenges to extract useful biophysics via both Stokes and Mueller matrix analyses. In this talk, I will highlight our ongoing studies of tissue birefringence in histology-like thin-sample transmission geometry (potential applications for breast and colorectal cancer), and in thick-tissue reflection geometry (potential applications for intraoperative surgical guidance). Enabling technology approaches, preclinical results, and selected patient studies will be highlighted

Conference Presentation

Citation Download Citation

I. Alex Vitkin "Photon mayhem: polarized light for structural and functional assessment of biological tissues", Proc. SPIE PC12690, Polarization Science and Remote Sensing XI, PC1269003 (5 October 2023); https://doi.org/10.1117/12.2683831

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available